High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer

Inflammatory breast cancer (IBC) is an aggressive form of breast cancer with a poor prognosis. Here the authors report the characterization of a human IBC cell line recapitulating the clinical and histopathological features of the human disease, and implicating its high level of CCL2 in macrophage i...

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Autores principales:	Anita Rogic, Ila Pant, Luca Grumolato, Ruben Fernandez-Rodriguez, Andrew Edwards, Suvendu Das, Aaron Sun, Shen Yao, Rui Qiao, Shabnam Jaffer, Ravi Sachidanandam, Guray Akturk, Rosa Karlic, Mihaela Skobe, Stuart A. Aaronson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/178a7e049b6748368cce8de609f3ab95
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spelling	oai:doaj.org-article:178a7e049b6748368cce8de609f3ab952021-11-28T12:31:37ZHigh endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer10.1038/s41467-021-27108-82041-1723https://doaj.org/article/178a7e049b6748368cce8de609f3ab952021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27108-8https://doaj.org/toc/2041-1723Inflammatory breast cancer (IBC) is an aggressive form of breast cancer with a poor prognosis. Here the authors report the characterization of a human IBC cell line recapitulating the clinical and histopathological features of the human disease, and implicating its high level of CCL2 in macrophage infiltration and tumor progression.Anita RogicIla PantLuca GrumolatoRuben Fernandez-RodriguezAndrew EdwardsSuvendu DasAaron SunShen YaoRui QiaoShabnam JafferRavi SachidanandamGuray AkturkRosa KarlicMihaela SkobeStuart A. AaronsonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anita Rogic Ila Pant Luca Grumolato Ruben Fernandez-Rodriguez Andrew Edwards Suvendu Das Aaron Sun Shen Yao Rui Qiao Shabnam Jaffer Ravi Sachidanandam Guray Akturk Rosa Karlic Mihaela Skobe Stuart A. Aaronson High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer
description	Inflammatory breast cancer (IBC) is an aggressive form of breast cancer with a poor prognosis. Here the authors report the characterization of a human IBC cell line recapitulating the clinical and histopathological features of the human disease, and implicating its high level of CCL2 in macrophage infiltration and tumor progression.
format	article
author	Anita Rogic Ila Pant Luca Grumolato Ruben Fernandez-Rodriguez Andrew Edwards Suvendu Das Aaron Sun Shen Yao Rui Qiao Shabnam Jaffer Ravi Sachidanandam Guray Akturk Rosa Karlic Mihaela Skobe Stuart A. Aaronson
author_facet	Anita Rogic Ila Pant Luca Grumolato Ruben Fernandez-Rodriguez Andrew Edwards Suvendu Das Aaron Sun Shen Yao Rui Qiao Shabnam Jaffer Ravi Sachidanandam Guray Akturk Rosa Karlic Mihaela Skobe Stuart A. Aaronson
author_sort	Anita Rogic
title	High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer
title_short	High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer
title_full	High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer
title_fullStr	High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer
title_full_unstemmed	High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer
title_sort	high endogenous ccl2 expression promotes the aggressive phenotype of human inflammatory breast cancer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/178a7e049b6748368cce8de609f3ab95
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High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer

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