Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles

Mutations in many centriolar protein-encoding genes cause primary microcephaly. Here the authors show that human microcephaly protein RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly, contributing to building full-length centrioles

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Autores principales:	Hsin-Yi Chen, Chien-Ting Wu, Chieh-Ju C. Tang, Yi-Nan Lin, Won-Jing Wang, Tang K. Tang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/17908d7c695d4446b67c1c19166df732
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spelling	oai:doaj.org-article:17908d7c695d4446b67c1c19166df7322021-12-02T13:57:55ZHuman microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles10.1038/s41467-017-00305-02041-1723https://doaj.org/article/17908d7c695d4446b67c1c19166df7322017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00305-0https://doaj.org/toc/2041-1723Mutations in many centriolar protein-encoding genes cause primary microcephaly. Here the authors show that human microcephaly protein RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly, contributing to building full-length centriolesHsin-Yi ChenChien-Ting WuChieh-Ju C. TangYi-Nan LinWon-Jing WangTang K. TangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hsin-Yi Chen Chien-Ting Wu Chieh-Ju C. Tang Yi-Nan Lin Won-Jing Wang Tang K. Tang Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles
description	Mutations in many centriolar protein-encoding genes cause primary microcephaly. Here the authors show that human microcephaly protein RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly, contributing to building full-length centrioles
format	article
author	Hsin-Yi Chen Chien-Ting Wu Chieh-Ju C. Tang Yi-Nan Lin Won-Jing Wang Tang K. Tang
author_facet	Hsin-Yi Chen Chien-Ting Wu Chieh-Ju C. Tang Yi-Nan Lin Won-Jing Wang Tang K. Tang
author_sort	Hsin-Yi Chen
title	Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles
title_short	Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles
title_full	Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles
title_fullStr	Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles
title_full_unstemmed	Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles
title_sort	human microcephaly protein rttn interacts with stil and is required to build full-length centrioles
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/17908d7c695d4446b67c1c19166df732
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Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles

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