Inflammation neuroscience: neuro‐immune crosstalk and interfaces

Abstract Inflammation is a key process in antimicrobial defence and tissue repair, and failure to properly regulate inflammation can result in tissue damage and death. Neural circuits play important roles throughout the course of an inflammatory response, and the neurophysiological and molecular mec...

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Auteurs principaux: Laura Tarnawski, Peder S Olofsson
Format: article
Langue:EN
Publié: Wiley 2021
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Accès en ligne:https://doaj.org/article/179518de5e504bc497562fa991d05422
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Résumé:Abstract Inflammation is a key process in antimicrobial defence and tissue repair, and failure to properly regulate inflammation can result in tissue damage and death. Neural circuits play important roles throughout the course of an inflammatory response, and the neurophysiological and molecular mechanisms are only partly understood. Here, we review key evidence for the neural regulation of inflammation and discuss emerging technologies to further map and harness this neurophysiology, a cornerstone in the rapidly evolving field of inflammation neuroscience.