Molecular determinants of magnolol targeting both RXRα and PPARγ.

Molecular determinants of magnolol targeting both RXRα and PPARγ.

Nuclear receptors retinoic X receptor α (RXRα) and peroxisome proliferator activated receptor γ (PPARγ) function potently in metabolic diseases, and are both important targets for anti-diabetic drugs. Coactivation of RXRα and PPARγ is believed to synergize their effects on glucose and lipid metaboli...

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Autores principales: Haitao Zhang, Xing Xu, Lili Chen, Jing Chen, Lihong Hu, Hualiang Jiang, Xu Shen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/17a2f9d2aa8e4466b8798141fe897eb7
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