Interpreting pathways to discover cancer driver genes with Moonlight

Identification of cancer driver genes, especially those that can act as tumour suppressors or oncogenes depending on context, remains a challenge. Here, the authors introduce Moonlight, a tool that integrates multi-omic data to address this challenge and identify numerous dual-role cancer genes.

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Detalles Bibliográficos
Autores principales:	Antonio Colaprico, Catharina Olsen, Matthew H. Bailey, Gabriel J. Odom, Thilde Terkelsen, Tiago C. Silva, André V. Olsen, Laura Cantini, Andrei Zinovyev, Emmanuel Barillot, Houtan Noushmehr, Gloria Bertoli, Isabella Castiglioni, Claudia Cava, Gianluca Bontempi, Xi Steven Chen, Elena Papaleo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/17a5443f838e4ce7b405503b7875ae15
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spelling	oai:doaj.org-article:17a5443f838e4ce7b405503b7875ae152021-12-02T15:39:29ZInterpreting pathways to discover cancer driver genes with Moonlight10.1038/s41467-019-13803-02041-1723https://doaj.org/article/17a5443f838e4ce7b405503b7875ae152020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13803-0https://doaj.org/toc/2041-1723Identification of cancer driver genes, especially those that can act as tumour suppressors or oncogenes depending on context, remains a challenge. Here, the authors introduce Moonlight, a tool that integrates multi-omic data to address this challenge and identify numerous dual-role cancer genes.Antonio ColapricoCatharina OlsenMatthew H. BaileyGabriel J. OdomThilde TerkelsenTiago C. SilvaAndré V. OlsenLaura CantiniAndrei ZinovyevEmmanuel BarillotHoutan NoushmehrGloria BertoliIsabella CastiglioniClaudia CavaGianluca BontempiXi Steven ChenElena PapaleoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Antonio Colaprico Catharina Olsen Matthew H. Bailey Gabriel J. Odom Thilde Terkelsen Tiago C. Silva André V. Olsen Laura Cantini Andrei Zinovyev Emmanuel Barillot Houtan Noushmehr Gloria Bertoli Isabella Castiglioni Claudia Cava Gianluca Bontempi Xi Steven Chen Elena Papaleo Interpreting pathways to discover cancer driver genes with Moonlight
description	Identification of cancer driver genes, especially those that can act as tumour suppressors or oncogenes depending on context, remains a challenge. Here, the authors introduce Moonlight, a tool that integrates multi-omic data to address this challenge and identify numerous dual-role cancer genes.
format	article
author	Antonio Colaprico Catharina Olsen Matthew H. Bailey Gabriel J. Odom Thilde Terkelsen Tiago C. Silva André V. Olsen Laura Cantini Andrei Zinovyev Emmanuel Barillot Houtan Noushmehr Gloria Bertoli Isabella Castiglioni Claudia Cava Gianluca Bontempi Xi Steven Chen Elena Papaleo
author_facet	Antonio Colaprico Catharina Olsen Matthew H. Bailey Gabriel J. Odom Thilde Terkelsen Tiago C. Silva André V. Olsen Laura Cantini Andrei Zinovyev Emmanuel Barillot Houtan Noushmehr Gloria Bertoli Isabella Castiglioni Claudia Cava Gianluca Bontempi Xi Steven Chen Elena Papaleo
author_sort	Antonio Colaprico
title	Interpreting pathways to discover cancer driver genes with Moonlight
title_short	Interpreting pathways to discover cancer driver genes with Moonlight
title_full	Interpreting pathways to discover cancer driver genes with Moonlight
title_fullStr	Interpreting pathways to discover cancer driver genes with Moonlight
title_full_unstemmed	Interpreting pathways to discover cancer driver genes with Moonlight
title_sort	interpreting pathways to discover cancer driver genes with moonlight
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/17a5443f838e4ce7b405503b7875ae15
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Interpreting pathways to discover cancer driver genes with Moonlight

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