Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells

Lantana camara Linn is a family of Verbenaceae which grows wild and is widespread in various both tropical and sub-tropical countries. Isolation essential oil of the L. camara leaves extracted by hydrodistillation and were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). The results of GC-M...

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Autores principales:	Suryati Suryati, Enda Desriansyah Aziz, Mai Efdi, Fatma Sri Wahyuni, Dira Hefni
Formato:	article
Lenguaje:	EN ID
Publicado:	Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas 2021
Materias:	lantana camara cytotoxic bslt assay mtt assay Chemistry QD1-999 Biochemistry QD415-436
Acceso en línea:	https://doaj.org/article/17a56670b46547ec9cacf557d57cf0b0
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spelling	oai:doaj.org-article:17a56670b46547ec9cacf557d57cf0b02021-12-02T18:16:53ZAnalysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells1978-628X2476-896010.25077/jrk.v12i1.364https://doaj.org/article/17a56670b46547ec9cacf557d57cf0b02021-04-01T00:00:00Zhttp://jrk.fmipa.unand.ac.id/index.php/jrk/article/view/364https://doaj.org/toc/1978-628Xhttps://doaj.org/toc/2476-8960Lantana camara Linn is a family of Verbenaceae which grows wild and is widespread in various both tropical and sub-tropical countries. Isolation essential oil of the L. camara leaves extracted by hydrodistillation and were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). The results of GC-MS analysis show isocaryophyllene (14.39%), ρ-cymene (8.17 %), β-cubebene (7.8 %), α-pinene (7.64 %), and β-elemene (5.51 %) as the main compound. The cytotoxic activity of the isolated essential oil was highly toxic both to Artemia salina shrimp larvae (LC50 15.92 µg/mL) and to breast cancer cells T-47D (IC50 10.67 µM).Suryati SuryatiEnda Desriansyah AzizMai EfdiFatma Sri WahyuniDira HefniDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalasarticlelantana camaracytotoxicbslt assaymtt assayChemistryQD1-999BiochemistryQD415-436ENIDJurnal Riset Kimia, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN ID
topic	lantana camara cytotoxic bslt assay mtt assay Chemistry QD1-999 Biochemistry QD415-436
spellingShingle	lantana camara cytotoxic bslt assay mtt assay Chemistry QD1-999 Biochemistry QD415-436 Suryati Suryati Enda Desriansyah Aziz Mai Efdi Fatma Sri Wahyuni Dira Hefni Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells
description	Lantana camara Linn is a family of Verbenaceae which grows wild and is widespread in various both tropical and sub-tropical countries. Isolation essential oil of the L. camara leaves extracted by hydrodistillation and were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). The results of GC-MS analysis show isocaryophyllene (14.39%), ρ-cymene (8.17 %), β-cubebene (7.8 %), α-pinene (7.64 %), and β-elemene (5.51 %) as the main compound. The cytotoxic activity of the isolated essential oil was highly toxic both to Artemia salina shrimp larvae (LC50 15.92 µg/mL) and to breast cancer cells T-47D (IC50 10.67 µM).
format	article
author	Suryati Suryati Enda Desriansyah Aziz Mai Efdi Fatma Sri Wahyuni Dira Hefni
author_facet	Suryati Suryati Enda Desriansyah Aziz Mai Efdi Fatma Sri Wahyuni Dira Hefni
author_sort	Suryati Suryati
title	Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells
title_short	Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells
title_full	Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells
title_fullStr	Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells
title_full_unstemmed	Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells
title_sort	analysis of the essential oil from lantana camara leaves and its cytotoxic potential against t-47d breast cancer cells
publisher	Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas
publishDate	2021
url	https://doaj.org/article/17a56670b46547ec9cacf557d57cf0b0
work_keys_str_mv	AT suryatisuryati analysisoftheessentialoilfromlantanacamaraleavesanditscytotoxicpotentialagainstt47dbreastcancercells AT endadesriansyahaziz analysisoftheessentialoilfromlantanacamaraleavesanditscytotoxicpotentialagainstt47dbreastcancercells AT maiefdi analysisoftheessentialoilfromlantanacamaraleavesanditscytotoxicpotentialagainstt47dbreastcancercells AT fatmasriwahyuni analysisoftheessentialoilfromlantanacamaraleavesanditscytotoxicpotentialagainstt47dbreastcancercells AT dirahefni analysisoftheessentialoilfromlantanacamaraleavesanditscytotoxicpotentialagainstt47dbreastcancercells
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Analysis of The Essential Oil from Lantana camara Leaves and Its Cytotoxic Potential Against T-47D Breast Cancer Cells

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