Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment

Tau, an intrinsically disordered axonal protein, binds to and regulates microtubule dynamics. Here, the authors use SAXS and electron microscopy to examine the architectures of microtubule bundles, including those mimicking microtubule fascicles in the axon initial segment.

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Autores principales:	Peter J. Chung, Chaeyeon Song, Joanna Deek, Herbert P. Miller, Youli Li, Myung Chul Choi, Leslie Wilson, Stuart C. Feinstein, Cyrus R. Safinya
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/17af19a67bf1441cbac6e6ba5dbdf4b4
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spelling	oai:doaj.org-article:17af19a67bf1441cbac6e6ba5dbdf4b42021-12-02T14:40:14ZTau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment10.1038/ncomms122782041-1723https://doaj.org/article/17af19a67bf1441cbac6e6ba5dbdf4b42016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12278https://doaj.org/toc/2041-1723Tau, an intrinsically disordered axonal protein, binds to and regulates microtubule dynamics. Here, the authors use SAXS and electron microscopy to examine the architectures of microtubule bundles, including those mimicking microtubule fascicles in the axon initial segment.Peter J. ChungChaeyeon SongJoanna DeekHerbert P. MillerYouli LiMyung Chul ChoiLeslie WilsonStuart C. FeinsteinCyrus R. SafinyaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peter J. Chung Chaeyeon Song Joanna Deek Herbert P. Miller Youli Li Myung Chul Choi Leslie Wilson Stuart C. Feinstein Cyrus R. Safinya Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
description	Tau, an intrinsically disordered axonal protein, binds to and regulates microtubule dynamics. Here, the authors use SAXS and electron microscopy to examine the architectures of microtubule bundles, including those mimicking microtubule fascicles in the axon initial segment.
format	article
author	Peter J. Chung Chaeyeon Song Joanna Deek Herbert P. Miller Youli Li Myung Chul Choi Leslie Wilson Stuart C. Feinstein Cyrus R. Safinya
author_facet	Peter J. Chung Chaeyeon Song Joanna Deek Herbert P. Miller Youli Li Myung Chul Choi Leslie Wilson Stuart C. Feinstein Cyrus R. Safinya
author_sort	Peter J. Chung
title	Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
title_short	Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
title_full	Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
title_fullStr	Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
title_full_unstemmed	Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
title_sort	tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/17af19a67bf1441cbac6e6ba5dbdf4b4
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Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment

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