Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease

Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease

Inflammatory bowel disease (IBD) has been linked to host-microbiota interactions. Here, the authors investigate mucosa-associated microbiota using endoscopically-targeted biopsies from inflamed and non-inflamed colon in patients with Crohn’s disease and ulcerative colitis, finding associations with...

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Autores principales: F. J. Ryan, A. M. Ahern, R. S. Fitzgerald, E. J. Laserna-Mendieta, E. M. Power, A. G. Clooney, K. W. O’Donoghue, P. J. McMurdie, S. Iwai, A. Crits-Christoph, D. Sheehan, C. Moran, B. Flemer, A. L. Zomer, A. Fanning, J. O’Callaghan, J. Walton, A. Temko, W. Stack, L. Jackson, S. A. Joyce, S. Melgar, T. Z. DeSantis, J. T. Bell, F. Shanahan, M. J. Claesson
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/17b3b06a64634f51813a1151f83b5396
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spelling oai:doaj.org-article:17b3b06a64634f51813a1151f83b53962021-12-02T17:31:24ZColonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease10.1038/s41467-020-15342-52041-1723https://doaj.org/article/17b3b06a64634f51813a1151f83b53962020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15342-5https://doaj.org/toc/2041-1723Inflammatory bowel disease (IBD) has been linked to host-microbiota interactions. Here, the authors investigate mucosa-associated microbiota using endoscopically-targeted biopsies from inflamed and non-inflamed colon in patients with Crohn’s disease and ulcerative colitis, finding associations with inflammation and host epigenomic alterations.F. J. RyanA. M. AhernR. S. FitzgeraldE. J. Laserna-MendietaE. M. PowerA. G. ClooneyK. W. O’DonoghueP. J. McMurdieS. IwaiA. Crits-ChristophD. SheehanC. MoranB. FlemerA. L. ZomerA. FanningJ. O’CallaghanJ. WaltonA. TemkoW. StackL. JacksonS. A. JoyceS. MelgarT. Z. DeSantisJ. T. BellF. ShanahanM. J. ClaessonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
F. J. Ryan
A. M. Ahern
R. S. Fitzgerald
E. J. Laserna-Mendieta
E. M. Power
A. G. Clooney
K. W. O’Donoghue
P. J. McMurdie
S. Iwai
A. Crits-Christoph
D. Sheehan
C. Moran
B. Flemer
A. L. Zomer
A. Fanning
J. O’Callaghan
J. Walton
A. Temko
W. Stack
L. Jackson
S. A. Joyce
S. Melgar
T. Z. DeSantis
J. T. Bell
F. Shanahan
M. J. Claesson
Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
description Inflammatory bowel disease (IBD) has been linked to host-microbiota interactions. Here, the authors investigate mucosa-associated microbiota using endoscopically-targeted biopsies from inflamed and non-inflamed colon in patients with Crohn’s disease and ulcerative colitis, finding associations with inflammation and host epigenomic alterations.
format article
author F. J. Ryan
A. M. Ahern
R. S. Fitzgerald
E. J. Laserna-Mendieta
E. M. Power
A. G. Clooney
K. W. O’Donoghue
P. J. McMurdie
S. Iwai
A. Crits-Christoph
D. Sheehan
C. Moran
B. Flemer
A. L. Zomer
A. Fanning
J. O’Callaghan
J. Walton
A. Temko
W. Stack
L. Jackson
S. A. Joyce
S. Melgar
T. Z. DeSantis
J. T. Bell
F. Shanahan
M. J. Claesson
author_facet F. J. Ryan
A. M. Ahern
R. S. Fitzgerald
E. J. Laserna-Mendieta
E. M. Power
A. G. Clooney
K. W. O’Donoghue
P. J. McMurdie
S. Iwai
A. Crits-Christoph
D. Sheehan
C. Moran
B. Flemer
A. L. Zomer
A. Fanning
J. O’Callaghan
J. Walton
A. Temko
W. Stack
L. Jackson
S. A. Joyce
S. Melgar
T. Z. DeSantis
J. T. Bell
F. Shanahan
M. J. Claesson
author_sort F. J. Ryan
title Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
title_short Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
title_full Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
title_fullStr Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
title_full_unstemmed Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
title_sort colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/17b3b06a64634f51813a1151f83b5396
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