Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum

This study presents an anatomical, neurophysiological and functional characterization of four distinct prefrontal populations that project to striatal and thalamic sub-regions. The authors show that each of these populations have a discrete role in the regulation of cognitive control.

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Autores principales: Sybren F. de Kloet, Bastiaan Bruinsma, Huub Terra, Tim S. Heistek, Emma M. J. Passchier, Alexandra R. van den Berg, Antonio Luchicchi, Rogier Min, Tommy Pattij, Huibert D. Mansvelder
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/17bef0b137494ed7848e3fdce6586f9f
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spelling oai:doaj.org-article:17bef0b137494ed7848e3fdce6586f9f2021-12-02T18:18:03ZBi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum10.1038/s41467-021-22260-72041-1723https://doaj.org/article/17bef0b137494ed7848e3fdce6586f9f2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22260-7https://doaj.org/toc/2041-1723This study presents an anatomical, neurophysiological and functional characterization of four distinct prefrontal populations that project to striatal and thalamic sub-regions. The authors show that each of these populations have a discrete role in the regulation of cognitive control.Sybren F. de KloetBastiaan BruinsmaHuub TerraTim S. HeistekEmma M. J. PasschierAlexandra R. van den BergAntonio LuchicchiRogier MinTommy PattijHuibert D. MansvelderNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sybren F. de Kloet
Bastiaan Bruinsma
Huub Terra
Tim S. Heistek
Emma M. J. Passchier
Alexandra R. van den Berg
Antonio Luchicchi
Rogier Min
Tommy Pattij
Huibert D. Mansvelder
Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
description This study presents an anatomical, neurophysiological and functional characterization of four distinct prefrontal populations that project to striatal and thalamic sub-regions. The authors show that each of these populations have a discrete role in the regulation of cognitive control.
format article
author Sybren F. de Kloet
Bastiaan Bruinsma
Huub Terra
Tim S. Heistek
Emma M. J. Passchier
Alexandra R. van den Berg
Antonio Luchicchi
Rogier Min
Tommy Pattij
Huibert D. Mansvelder
author_facet Sybren F. de Kloet
Bastiaan Bruinsma
Huub Terra
Tim S. Heistek
Emma M. J. Passchier
Alexandra R. van den Berg
Antonio Luchicchi
Rogier Min
Tommy Pattij
Huibert D. Mansvelder
author_sort Sybren F. de Kloet
title Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
title_short Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
title_full Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
title_fullStr Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
title_full_unstemmed Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
title_sort bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/17bef0b137494ed7848e3fdce6586f9f
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