Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
This study presents an anatomical, neurophysiological and functional characterization of four distinct prefrontal populations that project to striatal and thalamic sub-regions. The authors show that each of these populations have a discrete role in the regulation of cognitive control.
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Nature Portfolio
2021
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oai:doaj.org-article:17bef0b137494ed7848e3fdce6586f9f2021-12-02T18:18:03ZBi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum10.1038/s41467-021-22260-72041-1723https://doaj.org/article/17bef0b137494ed7848e3fdce6586f9f2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22260-7https://doaj.org/toc/2041-1723This study presents an anatomical, neurophysiological and functional characterization of four distinct prefrontal populations that project to striatal and thalamic sub-regions. The authors show that each of these populations have a discrete role in the regulation of cognitive control.Sybren F. de KloetBastiaan BruinsmaHuub TerraTim S. HeistekEmma M. J. PasschierAlexandra R. van den BergAntonio LuchicchiRogier MinTommy PattijHuibert D. MansvelderNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
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Science Q |
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Science Q Sybren F. de Kloet Bastiaan Bruinsma Huub Terra Tim S. Heistek Emma M. J. Passchier Alexandra R. van den Berg Antonio Luchicchi Rogier Min Tommy Pattij Huibert D. Mansvelder Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum |
description |
This study presents an anatomical, neurophysiological and functional characterization of four distinct prefrontal populations that project to striatal and thalamic sub-regions. The authors show that each of these populations have a discrete role in the regulation of cognitive control. |
format |
article |
author |
Sybren F. de Kloet Bastiaan Bruinsma Huub Terra Tim S. Heistek Emma M. J. Passchier Alexandra R. van den Berg Antonio Luchicchi Rogier Min Tommy Pattij Huibert D. Mansvelder |
author_facet |
Sybren F. de Kloet Bastiaan Bruinsma Huub Terra Tim S. Heistek Emma M. J. Passchier Alexandra R. van den Berg Antonio Luchicchi Rogier Min Tommy Pattij Huibert D. Mansvelder |
author_sort |
Sybren F. de Kloet |
title |
Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum |
title_short |
Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum |
title_full |
Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum |
title_fullStr |
Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum |
title_full_unstemmed |
Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum |
title_sort |
bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/17bef0b137494ed7848e3fdce6586f9f |
work_keys_str_mv |
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