BRAF mutations may identify a clinically distinct subset of glioblastoma

Abstract Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Prior studies examining the mutational landscape of GBM revealed recurrent alterations in genes that regulate the same growth control pathways. To this regard, ~ 40% of GBM harbor EGFR alterations, whereas BRAF v...

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Auteurs principaux: Samantha N. McNulty, Katherine E. Schwetye, Cole Ferguson, Chad E. Storer, George Ansstas, Albert H. Kim, David H. Gutmann, Joshua B. Rubin, Richard D. Head, Sonika Dahiya
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/17c10ebeab7c45f8a0a11cd5fc0b8d2c
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