Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7
The authors find that deletion from Schwann cells of an E3 ubiquitin ligase component called Fbxw7 leads to a phenotype reminiscent of myelination in the central nervous system where a single oligodendrocyte ensheaths multiple axons.
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Nature Portfolio
2019
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oai:doaj.org-article:17c998c1a86747189f3f8c1962a53a632021-12-02T16:51:01ZMyelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw710.1038/s41467-019-10881-y2041-1723https://doaj.org/article/17c998c1a86747189f3f8c1962a53a632019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10881-yhttps://doaj.org/toc/2041-1723The authors find that deletion from Schwann cells of an E3 ubiquitin ligase component called Fbxw7 leads to a phenotype reminiscent of myelination in the central nervous system where a single oligodendrocyte ensheaths multiple axons.Breanne L. HartyFernanda CoelhoSarah E. Pease-RaissiAmit MoghaSarah D. AckermanAmy L. HerbertRobert W. GereauJudith P. GoldenDavid A. LyonsJonah R. ChanKelly R. MonkNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019) |
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Science Q Breanne L. Harty Fernanda Coelho Sarah E. Pease-Raissi Amit Mogha Sarah D. Ackerman Amy L. Herbert Robert W. Gereau Judith P. Golden David A. Lyons Jonah R. Chan Kelly R. Monk Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7 |
description |
The authors find that deletion from Schwann cells of an E3 ubiquitin ligase component called Fbxw7 leads to a phenotype reminiscent of myelination in the central nervous system where a single oligodendrocyte ensheaths multiple axons. |
format |
article |
author |
Breanne L. Harty Fernanda Coelho Sarah E. Pease-Raissi Amit Mogha Sarah D. Ackerman Amy L. Herbert Robert W. Gereau Judith P. Golden David A. Lyons Jonah R. Chan Kelly R. Monk |
author_facet |
Breanne L. Harty Fernanda Coelho Sarah E. Pease-Raissi Amit Mogha Sarah D. Ackerman Amy L. Herbert Robert W. Gereau Judith P. Golden David A. Lyons Jonah R. Chan Kelly R. Monk |
author_sort |
Breanne L. Harty |
title |
Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7 |
title_short |
Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7 |
title_full |
Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7 |
title_fullStr |
Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7 |
title_full_unstemmed |
Myelinating Schwann cells ensheath multiple axons in the absence of E3 ligase component Fbxw7 |
title_sort |
myelinating schwann cells ensheath multiple axons in the absence of e3 ligase component fbxw7 |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/17c998c1a86747189f3f8c1962a53a63 |
work_keys_str_mv |
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