Blood meal-induced inhibition of vector-borne disease by transgenic microbiota
Vector alteration strategies are emerging as attractive tools for malaria transmission control. Here, Shane et al. engineer a bacterial strain, isolated from mosquitoes, to produce an antiplasmodial protein in the presence of blood meal, causing the mosquitoes to become refractory to Plasmodium infe...
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Nature Portfolio
2018
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oai:doaj.org-article:17ca97207de14ea1b64113b250b9bd832021-12-02T15:33:46ZBlood meal-induced inhibition of vector-borne disease by transgenic microbiota10.1038/s41467-018-06580-92041-1723https://doaj.org/article/17ca97207de14ea1b64113b250b9bd832018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06580-9https://doaj.org/toc/2041-1723Vector alteration strategies are emerging as attractive tools for malaria transmission control. Here, Shane et al. engineer a bacterial strain, isolated from mosquitoes, to produce an antiplasmodial protein in the presence of blood meal, causing the mosquitoes to become refractory to Plasmodium infection.Jackie L. ShaneChristina L. GroganCaroline CwalinaDavid J. LampeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q |
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Science Q Jackie L. Shane Christina L. Grogan Caroline Cwalina David J. Lampe Blood meal-induced inhibition of vector-borne disease by transgenic microbiota |
description |
Vector alteration strategies are emerging as attractive tools for malaria transmission control. Here, Shane et al. engineer a bacterial strain, isolated from mosquitoes, to produce an antiplasmodial protein in the presence of blood meal, causing the mosquitoes to become refractory to Plasmodium infection. |
format |
article |
author |
Jackie L. Shane Christina L. Grogan Caroline Cwalina David J. Lampe |
author_facet |
Jackie L. Shane Christina L. Grogan Caroline Cwalina David J. Lampe |
author_sort |
Jackie L. Shane |
title |
Blood meal-induced inhibition of vector-borne disease by transgenic microbiota |
title_short |
Blood meal-induced inhibition of vector-borne disease by transgenic microbiota |
title_full |
Blood meal-induced inhibition of vector-borne disease by transgenic microbiota |
title_fullStr |
Blood meal-induced inhibition of vector-borne disease by transgenic microbiota |
title_full_unstemmed |
Blood meal-induced inhibition of vector-borne disease by transgenic microbiota |
title_sort |
blood meal-induced inhibition of vector-borne disease by transgenic microbiota |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/17ca97207de14ea1b64113b250b9bd83 |
work_keys_str_mv |
AT jackielshane bloodmealinducedinhibitionofvectorbornediseasebytransgenicmicrobiota AT christinalgrogan bloodmealinducedinhibitionofvectorbornediseasebytransgenicmicrobiota AT carolinecwalina bloodmealinducedinhibitionofvectorbornediseasebytransgenicmicrobiota AT davidjlampe bloodmealinducedinhibitionofvectorbornediseasebytransgenicmicrobiota |
_version_ |
1718387007659442176 |