Visual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases

Roopa Vemala, Bhaskar Gupta, Sobha SivaprasadLaser and Retinal Research Unit, King&rsquo;s College Hospital, London SE5 9RS, UKIntroduction: Neovascular age related macular degeneration (AMD) is relatively uncommon in the black population. We report the 12-month outcome of ranibizumab therap...

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Autores principales:	Roopa Vemala, Bhaskar Gupta, Sobha Sivaprasad
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/17cca5c20521423f9a335a6988e57ffd
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spelling	oai:doaj.org-article:17cca5c20521423f9a335a6988e57ffd2021-12-02T03:18:35ZVisual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases1177-54671177-5483https://doaj.org/article/17cca5c20521423f9a335a6988e57ffd2010-08-01T00:00:00Zhttp://www.dovepress.com/visual-outcome-of-ranibizumab-therapy-for-neovascular-age-related-macu-a5003https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Roopa Vemala, Bhaskar Gupta, Sobha SivaprasadLaser and Retinal Research Unit, King&rsquo;s College Hospital, London SE5 9RS, UKIntroduction: Neovascular age related macular degeneration (AMD) is relatively uncommon in the black population. We report the 12-month outcome of ranibizumab therapy in five black patients with choroidal neovascular membrane (CNV) secondary to AMD.Material and methods: Retrospective analysis of a prospective audit database maintained for all patients on ranibizumab therapy in a retinal specialist unit that caters to a multi-ethnic cohort in London, United Kingdom.Results: At 12 months, all the 5 patients maintained stable vision (loss of less than 15 ETDRS letters). However, none of them gained more than 15 ETDRS letters. All eyes showed early subretinal fibrosis while 2 patients showed extended areas of retinal pigment atrophy.Conclusion: Our case studies indicate that ranibizumab stabilizes the vision in black patients with CNV secondary to AMD but they tend to develop early subretinal fibrosis and retinal pigment atrophy.Keywords: choroidal neovascular membrane, Afro-Caribbean, blacks Roopa VemalaBhaskar GuptaSobha SivaprasadDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 913-916 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Roopa Vemala Bhaskar Gupta Sobha Sivaprasad Visual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases
description	Roopa Vemala, Bhaskar Gupta, Sobha SivaprasadLaser and Retinal Research Unit, King&rsquo;s College Hospital, London SE5 9RS, UKIntroduction: Neovascular age related macular degeneration (AMD) is relatively uncommon in the black population. We report the 12-month outcome of ranibizumab therapy in five black patients with choroidal neovascular membrane (CNV) secondary to AMD.Material and methods: Retrospective analysis of a prospective audit database maintained for all patients on ranibizumab therapy in a retinal specialist unit that caters to a multi-ethnic cohort in London, United Kingdom.Results: At 12 months, all the 5 patients maintained stable vision (loss of less than 15 ETDRS letters). However, none of them gained more than 15 ETDRS letters. All eyes showed early subretinal fibrosis while 2 patients showed extended areas of retinal pigment atrophy.Conclusion: Our case studies indicate that ranibizumab stabilizes the vision in black patients with CNV secondary to AMD but they tend to develop early subretinal fibrosis and retinal pigment atrophy.Keywords: choroidal neovascular membrane, Afro-Caribbean, blacks
format	article
author	Roopa Vemala Bhaskar Gupta Sobha Sivaprasad
author_facet	Roopa Vemala Bhaskar Gupta Sobha Sivaprasad
author_sort	Roopa Vemala
title	Visual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases
title_short	Visual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases
title_full	Visual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases
title_fullStr	Visual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases
title_full_unstemmed	Visual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases
title_sort	visual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/17cca5c20521423f9a335a6988e57ffd
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Visual outcome of ranibizumab therapy for neovascular age related macular degeneration in the black population: a report of five cases

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