Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase

Type 2 topoisomerases alter DNA supercoiling by an ATP-dependent reaction involving DNA passage through a cleaved DNA duplex. Here the authors present the crystal structure of the ParE ATPase domains of S. pneumoniae topoisomerase IV, in complex with a captured DNA oligonucleotide.

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Autores principales:	Ivan Laponogov, Xiao-Su Pan, Dennis A. Veselkov, Galyna B. Skamrova, Trishant R. Umrekar, L. Mark Fisher, Mark R. Sanderson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/17d01b766de84ee880df3e914677978c
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spelling	oai:doaj.org-article:17d01b766de84ee880df3e914677978c2021-12-02T17:31:58ZTrapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase10.1038/s41467-018-05005-x2041-1723https://doaj.org/article/17d01b766de84ee880df3e914677978c2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05005-xhttps://doaj.org/toc/2041-1723Type 2 topoisomerases alter DNA supercoiling by an ATP-dependent reaction involving DNA passage through a cleaved DNA duplex. Here the authors present the crystal structure of the ParE ATPase domains of S. pneumoniae topoisomerase IV, in complex with a captured DNA oligonucleotide.Ivan LaponogovXiao-Su PanDennis A. VeselkovGalyna B. SkamrovaTrishant R. UmrekarL. Mark FisherMark R. SandersonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ivan Laponogov Xiao-Su Pan Dennis A. Veselkov Galyna B. Skamrova Trishant R. Umrekar L. Mark Fisher Mark R. Sanderson Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase
description	Type 2 topoisomerases alter DNA supercoiling by an ATP-dependent reaction involving DNA passage through a cleaved DNA duplex. Here the authors present the crystal structure of the ParE ATPase domains of S. pneumoniae topoisomerase IV, in complex with a captured DNA oligonucleotide.
format	article
author	Ivan Laponogov Xiao-Su Pan Dennis A. Veselkov Galyna B. Skamrova Trishant R. Umrekar L. Mark Fisher Mark R. Sanderson
author_facet	Ivan Laponogov Xiao-Su Pan Dennis A. Veselkov Galyna B. Skamrova Trishant R. Umrekar L. Mark Fisher Mark R. Sanderson
author_sort	Ivan Laponogov
title	Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase
title_short	Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase
title_full	Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase
title_fullStr	Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase
title_full_unstemmed	Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase
title_sort	trapping of the transport-segment dna by the atpase domains of a type ii topoisomerase
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/17d01b766de84ee880df3e914677978c
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Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase

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