Update on the use of pramipexole in the treatment of Parkinson’s disease
Radu ConstantinescuDepartment of Neurology, Sahlgrenska University Hospital, 413 45 Göteborg, SwedenAbstract: Pramipexole is a non-ergot dopamine agonist shown to be efficacious in the treatment of Parkinson’s disease (PD). This review addresses the literature concerning p...
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Dove Medical Press
2008
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oai:doaj.org-article:17db5ca1eeb748cd82866c37b72f19e42021-12-02T03:02:30ZUpdate on the use of pramipexole in the treatment of Parkinson’s disease1176-63281178-2021https://doaj.org/article/17db5ca1eeb748cd82866c37b72f19e42008-04-01T00:00:00Zhttp://www.dovepress.com/update-on-the-use-of-pramipexole-in-the-treatment-of-parkinsonrsquos-d-a1019https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Radu ConstantinescuDepartment of Neurology, Sahlgrenska University Hospital, 413 45 Göteborg, SwedenAbstract: Pramipexole is a non-ergot dopamine agonist shown to be efficacious in the treatment of Parkinson’s disease (PD). This review addresses the literature concerning pramipexole’s efficacy in treating motor and non-motor symptoms in PD, its impact on the development of dyskinesias and response fluctuations, the issue of neuroprotection, and the risk for developing adverse events such as increased somnolence, attacks of sudden onset of sleep, cardiac valvulopathy and impulse control disturbances.Keywords: pramipexole, Parkinson’s disease, efficacy, adverse events Radu ConstantinescuDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 2, Pp 337-352 (2008) |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Radu Constantinescu Update on the use of pramipexole in the treatment of Parkinson’s disease |
description |
Radu ConstantinescuDepartment of Neurology, Sahlgrenska University Hospital, 413 45 Göteborg, SwedenAbstract: Pramipexole is a non-ergot dopamine agonist shown to be efficacious in the treatment of Parkinson’s disease (PD). This review addresses the literature concerning pramipexole’s efficacy in treating motor and non-motor symptoms in PD, its impact on the development of dyskinesias and response fluctuations, the issue of neuroprotection, and the risk for developing adverse events such as increased somnolence, attacks of sudden onset of sleep, cardiac valvulopathy and impulse control disturbances.Keywords: pramipexole, Parkinson’s disease, efficacy, adverse events |
format |
article |
author |
Radu Constantinescu |
author_facet |
Radu Constantinescu |
author_sort |
Radu Constantinescu |
title |
Update on the use of pramipexole in the treatment of Parkinson’s disease |
title_short |
Update on the use of pramipexole in the treatment of Parkinson’s disease |
title_full |
Update on the use of pramipexole in the treatment of Parkinson’s disease |
title_fullStr |
Update on the use of pramipexole in the treatment of Parkinson’s disease |
title_full_unstemmed |
Update on the use of pramipexole in the treatment of Parkinson’s disease |
title_sort |
update on the use of pramipexole in the treatment of parkinson’s disease |
publisher |
Dove Medical Press |
publishDate |
2008 |
url |
https://doaj.org/article/17db5ca1eeb748cd82866c37b72f19e4 |
work_keys_str_mv |
AT raduconstantinescu updateontheuseofpramipexoleinthetreatmentofparkinsonamprsquosdisease |
_version_ |
1718401965598179328 |