The molecular basis of endothelial cell plasticity

Vascular endothelium possesses remarkable plasticity in response to cues from its surroundings, leading to great heterogeneity of endothelial cells in different vascular beds. Here the authors explain the molecular basis of endothelial plasticity during embryogenesis and in various diseases.

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Auteurs principaux: Elisabetta Dejana, Karen K. Hirschi, Michael Simons
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/17e23b4af4994c5abbea884369e38f4c
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spelling oai:doaj.org-article:17e23b4af4994c5abbea884369e38f4c2021-12-02T14:42:00ZThe molecular basis of endothelial cell plasticity10.1038/ncomms143612041-1723https://doaj.org/article/17e23b4af4994c5abbea884369e38f4c2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14361https://doaj.org/toc/2041-1723Vascular endothelium possesses remarkable plasticity in response to cues from its surroundings, leading to great heterogeneity of endothelial cells in different vascular beds. Here the authors explain the molecular basis of endothelial plasticity during embryogenesis and in various diseases.Elisabetta DejanaKaren K. HirschiMichael SimonsNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Elisabetta Dejana
Karen K. Hirschi
Michael Simons
The molecular basis of endothelial cell plasticity
description Vascular endothelium possesses remarkable plasticity in response to cues from its surroundings, leading to great heterogeneity of endothelial cells in different vascular beds. Here the authors explain the molecular basis of endothelial plasticity during embryogenesis and in various diseases.
format article
author Elisabetta Dejana
Karen K. Hirschi
Michael Simons
author_facet Elisabetta Dejana
Karen K. Hirschi
Michael Simons
author_sort Elisabetta Dejana
title The molecular basis of endothelial cell plasticity
title_short The molecular basis of endothelial cell plasticity
title_full The molecular basis of endothelial cell plasticity
title_fullStr The molecular basis of endothelial cell plasticity
title_full_unstemmed The molecular basis of endothelial cell plasticity
title_sort molecular basis of endothelial cell plasticity
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/17e23b4af4994c5abbea884369e38f4c
work_keys_str_mv AT elisabettadejana themolecularbasisofendothelialcellplasticity
AT karenkhirschi themolecularbasisofendothelialcellplasticity
AT michaelsimons themolecularbasisofendothelialcellplasticity
AT elisabettadejana molecularbasisofendothelialcellplasticity
AT karenkhirschi molecularbasisofendothelialcellplasticity
AT michaelsimons molecularbasisofendothelialcellplasticity
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