MEN1/Menin regulates milk protein synthesis through mTOR signaling in mammary epithelial cells
Abstract The MEN1 gene, which encodes the protein Menin, was investigated for its regulatory role in milk protein synthesis in mammary glands. Menin responds to nutrient and hormone levels via the PI3K/Akt/mTOR pathway. Bovine mammary epithelial cells and tissues were used as experimental models in...
Saved in:
Main Authors: | Honghui Li, Xue Liu, Zhonghua Wang, Xueyan Lin, Zhengui Yan, Qiaoqiao Cao, Meng Zhao, Kerong Shi |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/17e23bafc0d74c6687bcc4a2f4ea4914 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effects of Arginine concentration on the in vitro expression of Casein and mTOR pathway related genes in mammary epithelial cells from dairy cattle.
by: Mengzhi Wang, et al.
Published: (2014) -
Intracellular Staphylococcus aureus Infection Decreases Milk Protein Synthesis by Preventing Amino Acid Uptake in Bovine Mammary Epithelial Cells
by: Yuhao Chen, et al.
Published: (2021) -
MiR-485 targets the DTX4 gene to regulate milk fat synthesis in bovine mammary epithelial cells
by: Juan Liu, et al.
Published: (2021) -
Vitamin D Modulation of TRAIL Expression in Human Milk and Mammary Epithelial Cells
by: Yuvaraj Sambandam, et al.
Published: (2017) -
Genome-wide characterization of menin-dependent H3K4me3 reveals a specific role for menin in the regulation of genes implicated in MEN1-like tumors.
by: Sunita K Agarwal, et al.
Published: (2012)