Association between Maternal Exposure to Chemicals during Pregnancy and the Risk of Foetal Death: The Japan Environment and Children’s Study
Scarce knowledge is available on the relationship between maternal chemical exposure during pregnancy and foetal deaths. We studied the association of spontaneous abortions and stillbirths with occupational or daily maternal exposure to chemicals commonly used by pregnant women. Data from the Japan...
Guardado en:
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/17e2ecf0b62e40cd8c26e677db8b5ac4 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:17e2ecf0b62e40cd8c26e677db8b5ac4 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:17e2ecf0b62e40cd8c26e677db8b5ac42021-11-25T17:47:56ZAssociation between Maternal Exposure to Chemicals during Pregnancy and the Risk of Foetal Death: The Japan Environment and Children’s Study10.3390/ijerph1822117481660-46011661-7827https://doaj.org/article/17e2ecf0b62e40cd8c26e677db8b5ac42021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/22/11748https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601Scarce knowledge is available on the relationship between maternal chemical exposure during pregnancy and foetal deaths. We studied the association of spontaneous abortions and stillbirths with occupational or daily maternal exposure to chemicals commonly used by pregnant women. Data from the Japan Environment and Children’s Study (JECS), a nationwide prospective birth cohort study, were used. The participants of the study were asked about the frequency of their use of gasoline, pesticides, hair dye, and chlorine bleach during the first and the second to third trimesters of pregnancy. We investigated the relationship between the frequency of the use of chemicals and foetal death. Of the 104,065 foetuses, 923 (0.91%) were spontaneous abortions and 379 (0.37%) were stillbirths. Any type of exposure during the first trimester was not significantly associated with spontaneous abortions. Nevertheless, a more than weekly occupational use of hair dye from the first to the second/third trimester was significantly associated with stillbirth. The results of this study suggest that the frequent use of hair dye during pregnancy can have severe adverse effects on the foetus. These findings can help pregnant women, especially hairdressers, refrain from the continuous use of hair dyes.Tadao OokaSayaka HoriuchiRyoji ShinoharaReiji KojimaYuka AkiyamaKunio MiyakeSanae OtawaHiroshi YokomichiZentaro Yamagataon behalf of the Japan Environment and Children’s Study GroupMDPI AGarticlefoetal deathhair dyestillbirthspontaneous abortionpregnancymaternal exposureMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11748, p 11748 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
foetal death hair dye stillbirth spontaneous abortion pregnancy maternal exposure Medicine R |
| spellingShingle |
foetal death hair dye stillbirth spontaneous abortion pregnancy maternal exposure Medicine R Tadao Ooka Sayaka Horiuchi Ryoji Shinohara Reiji Kojima Yuka Akiyama Kunio Miyake Sanae Otawa Hiroshi Yokomichi Zentaro Yamagata on behalf of the Japan Environment and Children’s Study Group Association between Maternal Exposure to Chemicals during Pregnancy and the Risk of Foetal Death: The Japan Environment and Children’s Study |
| description |
Scarce knowledge is available on the relationship between maternal chemical exposure during pregnancy and foetal deaths. We studied the association of spontaneous abortions and stillbirths with occupational or daily maternal exposure to chemicals commonly used by pregnant women. Data from the Japan Environment and Children’s Study (JECS), a nationwide prospective birth cohort study, were used. The participants of the study were asked about the frequency of their use of gasoline, pesticides, hair dye, and chlorine bleach during the first and the second to third trimesters of pregnancy. We investigated the relationship between the frequency of the use of chemicals and foetal death. Of the 104,065 foetuses, 923 (0.91%) were spontaneous abortions and 379 (0.37%) were stillbirths. Any type of exposure during the first trimester was not significantly associated with spontaneous abortions. Nevertheless, a more than weekly occupational use of hair dye from the first to the second/third trimester was significantly associated with stillbirth. The results of this study suggest that the frequent use of hair dye during pregnancy can have severe adverse effects on the foetus. These findings can help pregnant women, especially hairdressers, refrain from the continuous use of hair dyes. |
| format |
article |
| author |
Tadao Ooka Sayaka Horiuchi Ryoji Shinohara Reiji Kojima Yuka Akiyama Kunio Miyake Sanae Otawa Hiroshi Yokomichi Zentaro Yamagata on behalf of the Japan Environment and Children’s Study Group |
| author_facet |
Tadao Ooka Sayaka Horiuchi Ryoji Shinohara Reiji Kojima Yuka Akiyama Kunio Miyake Sanae Otawa Hiroshi Yokomichi Zentaro Yamagata on behalf of the Japan Environment and Children’s Study Group |
| author_sort |
Tadao Ooka |
| title |
Association between Maternal Exposure to Chemicals during Pregnancy and the Risk of Foetal Death: The Japan Environment and Children’s Study |
| title_short |
Association between Maternal Exposure to Chemicals during Pregnancy and the Risk of Foetal Death: The Japan Environment and Children’s Study |
| title_full |
Association between Maternal Exposure to Chemicals during Pregnancy and the Risk of Foetal Death: The Japan Environment and Children’s Study |
| title_fullStr |
Association between Maternal Exposure to Chemicals during Pregnancy and the Risk of Foetal Death: The Japan Environment and Children’s Study |
| title_full_unstemmed |
Association between Maternal Exposure to Chemicals during Pregnancy and the Risk of Foetal Death: The Japan Environment and Children’s Study |
| title_sort |
association between maternal exposure to chemicals during pregnancy and the risk of foetal death: the japan environment and children’s study |
| publisher |
MDPI AG |
| publishDate |
2021 |
| url |
https://doaj.org/article/17e2ecf0b62e40cd8c26e677db8b5ac4 |
| work_keys_str_mv |
AT tadaoooka associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy AT sayakahoriuchi associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy AT ryojishinohara associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy AT reijikojima associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy AT yukaakiyama associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy AT kuniomiyake associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy AT sanaeotawa associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy AT hiroshiyokomichi associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy AT zentaroyamagata associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy AT onbehalfofthejapanenvironmentandchildrensstudygroup associationbetweenmaternalexposuretochemicalsduringpregnancyandtheriskoffoetaldeaththejapanenvironmentandchildrensstudy |
| _version_ |
1718411969296334848 |