OXA-48-Mediated Ceftazidime-Avibactam Resistance Is Associated with Evolutionary Trade-Offs

ABSTRACT Infections due to carbapenemase-producing Gram-negative pathogens are associated with limited treatment options and consequently lead to increased mortality and morbidity. In response, combinations of existing β-lactams and novel β-lactamase inhibitors, such as ceftazidime-avibactam (CAZ-AV...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Christopher Fröhlich, Vidar Sørum, Ane Molden Thomassen, Pål Jarle Johnsen, Hanna-Kirsti S. Leiros, Ørjan Samuelsen
Format: article
Langue:EN
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://doaj.org/article/17e5f96f1a714a89b3f195058f277abd
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!