The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue
Chlorpyrifos is a widely-used pesticide and a common residue on vegetables and fruits. Here the authors show that at non-neurotoxic doses, chlorpyrifos reduces energy expenditure, by inhibiting diet induced thermogenesis, and promotes obesity and insulin resistance.
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Nature Portfolio
2021
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oai:doaj.org-article:17efe75eaf7346188e0d2025067371da2021-12-02T18:53:15ZThe pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue10.1038/s41467-021-25384-y2041-1723https://doaj.org/article/17efe75eaf7346188e0d2025067371da2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25384-yhttps://doaj.org/toc/2041-1723Chlorpyrifos is a widely-used pesticide and a common residue on vegetables and fruits. Here the authors show that at non-neurotoxic doses, chlorpyrifos reduces energy expenditure, by inhibiting diet induced thermogenesis, and promotes obesity and insulin resistance.Bo WangEvangelia E. TsakiridisShuman ZhangAndrea LlanosEric M. DesjardinsJulian M. YabutAlexander E. GreenEmily A. DayBrennan K. SmithJames S. V. LallyJianhan WuAmogelang R. RaphenyaKrishna A. SrinivasanAndrew G. McArthurShingo KajimuraJagdish Suresh PatelMichael G. WadeKatherine M. MorrisonAlison C. HollowayGregory R. SteinbergNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
| institution |
DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Bo Wang Evangelia E. Tsakiridis Shuman Zhang Andrea Llanos Eric M. Desjardins Julian M. Yabut Alexander E. Green Emily A. Day Brennan K. Smith James S. V. Lally Jianhan Wu Amogelang R. Raphenya Krishna A. Srinivasan Andrew G. McArthur Shingo Kajimura Jagdish Suresh Patel Michael G. Wade Katherine M. Morrison Alison C. Holloway Gregory R. Steinberg The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue |
| description |
Chlorpyrifos is a widely-used pesticide and a common residue on vegetables and fruits. Here the authors show that at non-neurotoxic doses, chlorpyrifos reduces energy expenditure, by inhibiting diet induced thermogenesis, and promotes obesity and insulin resistance. |
| format |
article |
| author |
Bo Wang Evangelia E. Tsakiridis Shuman Zhang Andrea Llanos Eric M. Desjardins Julian M. Yabut Alexander E. Green Emily A. Day Brennan K. Smith James S. V. Lally Jianhan Wu Amogelang R. Raphenya Krishna A. Srinivasan Andrew G. McArthur Shingo Kajimura Jagdish Suresh Patel Michael G. Wade Katherine M. Morrison Alison C. Holloway Gregory R. Steinberg |
| author_facet |
Bo Wang Evangelia E. Tsakiridis Shuman Zhang Andrea Llanos Eric M. Desjardins Julian M. Yabut Alexander E. Green Emily A. Day Brennan K. Smith James S. V. Lally Jianhan Wu Amogelang R. Raphenya Krishna A. Srinivasan Andrew G. McArthur Shingo Kajimura Jagdish Suresh Patel Michael G. Wade Katherine M. Morrison Alison C. Holloway Gregory R. Steinberg |
| author_sort |
Bo Wang |
| title |
The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue |
| title_short |
The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue |
| title_full |
The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue |
| title_fullStr |
The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue |
| title_full_unstemmed |
The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue |
| title_sort |
pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/17efe75eaf7346188e0d2025067371da |
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