Coronavirus (SARS-CoV-2): Preventions, keys to diagnosis and treatment of SARS-CoV-2

World Health Organization (WHO) is gathering the latest scientific findings and knowledge on coronavirus disease (SARS-CoV-2) and compiling it in a database. WHO update the database daily from searches of bibliographic databases, hand searches of the table of contents of relevant journals, and the a...

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Autores principales:	Kuldeep Singh Patel, Jagdish Chandra Rathi, Karuna Raghuvanshi, Neerupma Dhiman
Formato:	article
Lenguaje:	EN
Publicado:	Emergency Department of Hospital San Pedro (Logroño, Spain) 2020
Materias:	sars-cov-2 coronavirus antivirals Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/17fa0259a7f14f9ab050f3a9f9836ef4
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spelling	oai:doaj.org-article:17fa0259a7f14f9ab050f3a9f9836ef42021-12-02T19:15:07ZCoronavirus (SARS-CoV-2): Preventions, keys to diagnosis and treatment of SARS-CoV-210.5281/zenodo.37152662695-5075https://doaj.org/article/17fa0259a7f14f9ab050f3a9f9836ef42020-03-01T00:00:00Zhttps://doi.org/10.5281/zenodo.3715266https://doaj.org/toc/2695-5075World Health Organization (WHO) is gathering the latest scientific findings and knowledge on coronavirus disease (SARS-CoV-2) and compiling it in a database. WHO update the database daily from searches of bibliographic databases, hand searches of the table of contents of relevant journals, and the addition of other relevant scientific articles that come to our attention. The entries in the database may not be exhaustive and new research will be added regularly. Nobel coronavirus investigators, the recognition of a nobel coronavirus as the cause of severe acute respiratory syndrome (SARS) was certainly remarkable, yet perhaps not surprising. Advances in the biology of coronaviruses have resulted in greater understanding of their capacity for adaptation to new environments, transspecies infection, and emergence of new diseases. New tools of cell and molecular biology have led to increased understanding of intracellular replication and viral cell biology, and the advent in the past five years of reverse genetic approaches to study coronaviruses has made it possible to begin to define the determinants of viral replication, transpecies adaptation, and human disease. This summary will discuss the basic life cycle and replication of the well-studied coronavirus, mouse hepatitis virus (MHV), identifying the unique characteristics of coronavirus biology and highlighting critical points where research has made significant advances, and which might represent targets for antivirals or vaccines. Areas where rapid progress has been made in SCoV research will be described. Finally, areas of need for research in coronavirus replication, genetics, and pathogenesis will be summarized.Kuldeep Singh PatelJagdish Chandra RathiKaruna RaghuvanshiNeerupma DhimanEmergency Department of Hospital San Pedro (Logroño, Spain)articlesars-cov-2coronavirusantiviralsMedicine (General)R5-920ENIberoamerican Journal of Medicine, Vol 2, Iss 2, Pp 87-99 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	sars-cov-2 coronavirus antivirals Medicine (General) R5-920
spellingShingle	sars-cov-2 coronavirus antivirals Medicine (General) R5-920 Kuldeep Singh Patel Jagdish Chandra Rathi Karuna Raghuvanshi Neerupma Dhiman Coronavirus (SARS-CoV-2): Preventions, keys to diagnosis and treatment of SARS-CoV-2
description	World Health Organization (WHO) is gathering the latest scientific findings and knowledge on coronavirus disease (SARS-CoV-2) and compiling it in a database. WHO update the database daily from searches of bibliographic databases, hand searches of the table of contents of relevant journals, and the addition of other relevant scientific articles that come to our attention. The entries in the database may not be exhaustive and new research will be added regularly. Nobel coronavirus investigators, the recognition of a nobel coronavirus as the cause of severe acute respiratory syndrome (SARS) was certainly remarkable, yet perhaps not surprising. Advances in the biology of coronaviruses have resulted in greater understanding of their capacity for adaptation to new environments, transspecies infection, and emergence of new diseases. New tools of cell and molecular biology have led to increased understanding of intracellular replication and viral cell biology, and the advent in the past five years of reverse genetic approaches to study coronaviruses has made it possible to begin to define the determinants of viral replication, transpecies adaptation, and human disease. This summary will discuss the basic life cycle and replication of the well-studied coronavirus, mouse hepatitis virus (MHV), identifying the unique characteristics of coronavirus biology and highlighting critical points where research has made significant advances, and which might represent targets for antivirals or vaccines. Areas where rapid progress has been made in SCoV research will be described. Finally, areas of need for research in coronavirus replication, genetics, and pathogenesis will be summarized.
format	article
author	Kuldeep Singh Patel Jagdish Chandra Rathi Karuna Raghuvanshi Neerupma Dhiman
author_facet	Kuldeep Singh Patel Jagdish Chandra Rathi Karuna Raghuvanshi Neerupma Dhiman
author_sort	Kuldeep Singh Patel
title	Coronavirus (SARS-CoV-2): Preventions, keys to diagnosis and treatment of SARS-CoV-2
title_short	Coronavirus (SARS-CoV-2): Preventions, keys to diagnosis and treatment of SARS-CoV-2
title_full	Coronavirus (SARS-CoV-2): Preventions, keys to diagnosis and treatment of SARS-CoV-2
title_fullStr	Coronavirus (SARS-CoV-2): Preventions, keys to diagnosis and treatment of SARS-CoV-2
title_full_unstemmed	Coronavirus (SARS-CoV-2): Preventions, keys to diagnosis and treatment of SARS-CoV-2
title_sort	coronavirus (sars-cov-2): preventions, keys to diagnosis and treatment of sars-cov-2
publisher	Emergency Department of Hospital San Pedro (Logroño, Spain)
publishDate	2020
url	https://doaj.org/article/17fa0259a7f14f9ab050f3a9f9836ef4
work_keys_str_mv	AT kuldeepsinghpatel coronavirussarscov2preventionskeystodiagnosisandtreatmentofsarscov2 AT jagdishchandrarathi coronavirussarscov2preventionskeystodiagnosisandtreatmentofsarscov2 AT karunaraghuvanshi coronavirussarscov2preventionskeystodiagnosisandtreatmentofsarscov2 AT neerupmadhiman coronavirussarscov2preventionskeystodiagnosisandtreatmentofsarscov2
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Coronavirus (SARS-CoV-2): Preventions, keys to diagnosis and treatment of SARS-CoV-2

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