Pathway engineering in yeast for synthesizing the complex polyketide bikaverin

Bikaverin is a fungal-derived tetracyclic polyketide with antibiotic, antifungal and anticancer properties. Here, the authors employ various pathway engineering strategies to achieve high level production of bikaverin in baker’s yeast.

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Autores principales:	Meng Zhao, Yu Zhao, Mingdong Yao, Hala Iqbal, Qi Hu, Hong Liu, Bin Qiao, Chun Li, Christine A. S. Skovbjerg, Jens Christian Nielsen, Jens Nielsen, Rasmus J. N. Frandsen, Yingjin Yuan, Jef D. Boeke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/17ffb0d3b9194b9cba9476bf3dd6a6d7
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spelling	oai:doaj.org-article:17ffb0d3b9194b9cba9476bf3dd6a6d72021-12-02T15:39:21ZPathway engineering in yeast for synthesizing the complex polyketide bikaverin10.1038/s41467-020-19984-32041-1723https://doaj.org/article/17ffb0d3b9194b9cba9476bf3dd6a6d72020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19984-3https://doaj.org/toc/2041-1723Bikaverin is a fungal-derived tetracyclic polyketide with antibiotic, antifungal and anticancer properties. Here, the authors employ various pathway engineering strategies to achieve high level production of bikaverin in baker’s yeast.Meng ZhaoYu ZhaoMingdong YaoHala IqbalQi HuHong LiuBin QiaoChun LiChristine A. S. SkovbjergJens Christian NielsenJens NielsenRasmus J. N. FrandsenYingjin YuanJef D. BoekeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Meng Zhao Yu Zhao Mingdong Yao Hala Iqbal Qi Hu Hong Liu Bin Qiao Chun Li Christine A. S. Skovbjerg Jens Christian Nielsen Jens Nielsen Rasmus J. N. Frandsen Yingjin Yuan Jef D. Boeke Pathway engineering in yeast for synthesizing the complex polyketide bikaverin
description	Bikaverin is a fungal-derived tetracyclic polyketide with antibiotic, antifungal and anticancer properties. Here, the authors employ various pathway engineering strategies to achieve high level production of bikaverin in baker’s yeast.
format	article
author	Meng Zhao Yu Zhao Mingdong Yao Hala Iqbal Qi Hu Hong Liu Bin Qiao Chun Li Christine A. S. Skovbjerg Jens Christian Nielsen Jens Nielsen Rasmus J. N. Frandsen Yingjin Yuan Jef D. Boeke
author_facet	Meng Zhao Yu Zhao Mingdong Yao Hala Iqbal Qi Hu Hong Liu Bin Qiao Chun Li Christine A. S. Skovbjerg Jens Christian Nielsen Jens Nielsen Rasmus J. N. Frandsen Yingjin Yuan Jef D. Boeke
author_sort	Meng Zhao
title	Pathway engineering in yeast for synthesizing the complex polyketide bikaverin
title_short	Pathway engineering in yeast for synthesizing the complex polyketide bikaverin
title_full	Pathway engineering in yeast for synthesizing the complex polyketide bikaverin
title_fullStr	Pathway engineering in yeast for synthesizing the complex polyketide bikaverin
title_full_unstemmed	Pathway engineering in yeast for synthesizing the complex polyketide bikaverin
title_sort	pathway engineering in yeast for synthesizing the complex polyketide bikaverin
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/17ffb0d3b9194b9cba9476bf3dd6a6d7
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Pathway engineering in yeast for synthesizing the complex polyketide bikaverin

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