Inhibitory effect of TNF-α on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations.

Inhibitory effect of TNF-α on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations.

<h4>Background</h4>The liver stages of malaria parasites are inhibited by cytokines such as interferon-γ or Interleukin (IL)-6. Binding of these cytokines to their receptors at the surface of the infected hepatocytes leads to the production of nitric oxide (NO) and radical oxygen interme...

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Main Authors: Nadya Depinay, Jean Francois Franetich, Anne Charlotte Grüner, Marjorie Mauduit, Jean-Marc Chavatte, Adrian J F Luty, Geert-Jan van Gemert, Robert W Sauerwein, Jean-Michel Siksik, Laurent Hannoun, Dominique Mazier, Georges Snounou, Laurent Rénia
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/18039d74296d45ac84cfab934fef6a55
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https://doaj.org/article/18039d74296d45ac84cfab934fef6a55

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