Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments
Tissue engineering is an emerging discipline that combines engineering and life sciences. It can construct functional biological structures in vivo or in vitro to replace native tissues or organs and minimize serious shortages of donor organs during tissue and organ reconstruction or transplantation...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:18040606b5144618a3c35d06168d29eb2021-11-08T07:18:47ZTissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments2296-418510.3389/fbioe.2021.662418https://doaj.org/article/18040606b5144618a3c35d06168d29eb2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fbioe.2021.662418/fullhttps://doaj.org/toc/2296-4185Tissue engineering is an emerging discipline that combines engineering and life sciences. It can construct functional biological structures in vivo or in vitro to replace native tissues or organs and minimize serious shortages of donor organs during tissue and organ reconstruction or transplantation. Organ transplantation has achieved success by using the tissue-engineered heart, liver, kidney, and other artificial organs, and the emergence of tissue-engineered bone also provides a new approach for the healing of human bone defects. In recent years, tissue engineering technology has gradually become an important technical method for dentistry research, and its application in stomatology-related research has also obtained impressive achievements. The purpose of this review is to summarize the research advances of tissue engineering and its application in stomatology. These aspects include tooth, periodontal, dental implant, cleft palate, oral and maxillofacial skin or mucosa, and oral and maxillofacial bone tissue engineering. In addition, this article also summarizes the commonly used cells, scaffolds, and growth factors in stomatology and discusses the limitations of tissue engineering in stomatology from the perspective of cells, scaffolds, and clinical applications.Lilan CaoHuiying SuMengying SiJing XuXin ChangJiajia LvJiajia LvYuankun ZhaiYuankun ZhaiFrontiers Media S.A.articletissue engineeringscaffoldsgrowth factorsperiodontaldental implantscleft palateBiotechnologyTP248.13-248.65ENFrontiers in Bioengineering and Biotechnology, Vol 9 (2021) |
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tissue engineering scaffolds growth factors periodontal dental implants cleft palate Biotechnology TP248.13-248.65 |
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tissue engineering scaffolds growth factors periodontal dental implants cleft palate Biotechnology TP248.13-248.65 Lilan Cao Huiying Su Mengying Si Jing Xu Xin Chang Jiajia Lv Jiajia Lv Yuankun Zhai Yuankun Zhai Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments |
description |
Tissue engineering is an emerging discipline that combines engineering and life sciences. It can construct functional biological structures in vivo or in vitro to replace native tissues or organs and minimize serious shortages of donor organs during tissue and organ reconstruction or transplantation. Organ transplantation has achieved success by using the tissue-engineered heart, liver, kidney, and other artificial organs, and the emergence of tissue-engineered bone also provides a new approach for the healing of human bone defects. In recent years, tissue engineering technology has gradually become an important technical method for dentistry research, and its application in stomatology-related research has also obtained impressive achievements. The purpose of this review is to summarize the research advances of tissue engineering and its application in stomatology. These aspects include tooth, periodontal, dental implant, cleft palate, oral and maxillofacial skin or mucosa, and oral and maxillofacial bone tissue engineering. In addition, this article also summarizes the commonly used cells, scaffolds, and growth factors in stomatology and discusses the limitations of tissue engineering in stomatology from the perspective of cells, scaffolds, and clinical applications. |
format |
article |
author |
Lilan Cao Huiying Su Mengying Si Jing Xu Xin Chang Jiajia Lv Jiajia Lv Yuankun Zhai Yuankun Zhai |
author_facet |
Lilan Cao Huiying Su Mengying Si Jing Xu Xin Chang Jiajia Lv Jiajia Lv Yuankun Zhai Yuankun Zhai |
author_sort |
Lilan Cao |
title |
Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments |
title_short |
Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments |
title_full |
Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments |
title_fullStr |
Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments |
title_full_unstemmed |
Tissue Engineering in Stomatology: A Review of Potential Approaches for Oral Disease Treatments |
title_sort |
tissue engineering in stomatology: a review of potential approaches for oral disease treatments |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doaj.org/article/18040606b5144618a3c35d06168d29eb |
work_keys_str_mv |
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