Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics

Sepsis can lead to multiple organ failure that could potentially be reflected by change in plasma protein abundance. Here the authors describe a proteomics strategy that allows the determination of plasma proteins tissue origin in a quantitative manner for use as biomarkers—illustrated in a mouse mo...

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Autores principales:	Erik Malmström, Ola Kilsgård, Simon Hauri, Emanuel Smeds, Heiko Herwald, Lars Malmström, Johan Malmström
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/180515b4471648a094ca8757685ed496
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spelling	oai:doaj.org-article:180515b4471648a094ca8757685ed4962021-12-02T17:33:22ZLarge-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics10.1038/ncomms102612041-1723https://doaj.org/article/180515b4471648a094ca8757685ed4962016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10261https://doaj.org/toc/2041-1723Sepsis can lead to multiple organ failure that could potentially be reflected by change in plasma protein abundance. Here the authors describe a proteomics strategy that allows the determination of plasma proteins tissue origin in a quantitative manner for use as biomarkers—illustrated in a mouse model of sepsis.Erik MalmströmOla KilsgårdSimon HauriEmanuel SmedsHeiko HerwaldLars MalmströmJohan MalmströmNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erik Malmström Ola Kilsgård Simon Hauri Emanuel Smeds Heiko Herwald Lars Malmström Johan Malmström Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics
description	Sepsis can lead to multiple organ failure that could potentially be reflected by change in plasma protein abundance. Here the authors describe a proteomics strategy that allows the determination of plasma proteins tissue origin in a quantitative manner for use as biomarkers—illustrated in a mouse model of sepsis.
format	article
author	Erik Malmström Ola Kilsgård Simon Hauri Emanuel Smeds Heiko Herwald Lars Malmström Johan Malmström
author_facet	Erik Malmström Ola Kilsgård Simon Hauri Emanuel Smeds Heiko Herwald Lars Malmström Johan Malmström
author_sort	Erik Malmström
title	Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics
title_short	Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics
title_full	Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics
title_fullStr	Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics
title_full_unstemmed	Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics
title_sort	large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/180515b4471648a094ca8757685ed496
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Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics

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