Circular RNA VANGL1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting miR-145-5p to regulate SOX4 in bladder cancer cells

Bladder cancer is a common malignancy in the world. It is reported that circular RNA VANGL1 (circ_VANGL1) was involved in bladder cancer progression. However, the functional role and molecular mechanism of circ_VANGL1 in bladder cancer were still unclear.

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Autores principales:	Zhu Jiangbo, Zhang Fei
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	circ_vangl1 mir-145-5p sox4 doxorubicin bladder cancer Medicine R
Acceso en línea:	https://doaj.org/article/18154db81fa24f4da38de71f8e376d0f
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spelling	oai:doaj.org-article:18154db81fa24f4da38de71f8e376d0f2021-12-05T14:10:54ZCircular RNA VANGL1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting miR-145-5p to regulate SOX4 in bladder cancer cells2391-546310.1515/med-2021-0299https://doaj.org/article/18154db81fa24f4da38de71f8e376d0f2021-07-01T00:00:00Zhttps://doi.org/10.1515/med-2021-0299https://doaj.org/toc/2391-5463Bladder cancer is a common malignancy in the world. It is reported that circular RNA VANGL1 (circ_VANGL1) was involved in bladder cancer progression. However, the functional role and molecular mechanism of circ_VANGL1 in bladder cancer were still unclear.Zhu JiangboZhang FeiDe Gruyterarticlecirc_vangl1mir-145-5psox4doxorubicinbladder cancerMedicineRENOpen Medicine, Vol 16, Iss 1, Pp 1010-1021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	circ_vangl1 mir-145-5p sox4 doxorubicin bladder cancer Medicine R
spellingShingle	circ_vangl1 mir-145-5p sox4 doxorubicin bladder cancer Medicine R Zhu Jiangbo Zhang Fei Circular RNA VANGL1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting miR-145-5p to regulate SOX4 in bladder cancer cells
description	Bladder cancer is a common malignancy in the world. It is reported that circular RNA VANGL1 (circ_VANGL1) was involved in bladder cancer progression. However, the functional role and molecular mechanism of circ_VANGL1 in bladder cancer were still unclear.
format	article
author	Zhu Jiangbo Zhang Fei
author_facet	Zhu Jiangbo Zhang Fei
author_sort	Zhu Jiangbo
title	Circular RNA VANGL1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting miR-145-5p to regulate SOX4 in bladder cancer cells
title_short	Circular RNA VANGL1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting miR-145-5p to regulate SOX4 in bladder cancer cells
title_full	Circular RNA VANGL1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting miR-145-5p to regulate SOX4 in bladder cancer cells
title_fullStr	Circular RNA VANGL1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting miR-145-5p to regulate SOX4 in bladder cancer cells
title_full_unstemmed	Circular RNA VANGL1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting miR-145-5p to regulate SOX4 in bladder cancer cells
title_sort	circular rna vangl1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting mir-145-5p to regulate sox4 in bladder cancer cells
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/18154db81fa24f4da38de71f8e376d0f
work_keys_str_mv	AT zhujiangbo circularrnavangl1knockdownsuppressedviabilitypromotedapoptosisandincreaseddoxorubicinsensitivitythroughtargetingmir1455ptoregulatesox4inbladdercancercells AT zhangfei circularrnavangl1knockdownsuppressedviabilitypromotedapoptosisandincreaseddoxorubicinsensitivitythroughtargetingmir1455ptoregulatesox4inbladdercancercells
_version_	1718371586230190080

Circular RNA VANGL1 knockdown suppressed viability, promoted apoptosis, and increased doxorubicin sensitivity through targeting miR-145-5p to regulate SOX4 in bladder cancer cells

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