Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts

Large population testing is a key step to controlling the COVID-19 pandemic. Here, the authors develop a targeted mass spectrometry system for peptide-based SARS-CoV-2 detection, allowing analysis of over 500 swab samples per day and enabling virus detection even after prolonged sample storage at ro...

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Autores principales: Karina Helena Morais Cardozo, Adriana Lebkuchen, Guilherme Gonçalves Okai, Rodrigo Andrade Schuch, Luciana Godoy Viana, Aline Nogueira Olive, Carolina dos Santos Lazari, Ana Maria Fraga, Celso Francisco Hernandes Granato, Maria Carolina Tostes Pintão, Valdemir Melechco Carvalho
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/181b7486d0ca47e2b97c7ebd8e67cab7
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spelling oai:doaj.org-article:181b7486d0ca47e2b97c7ebd8e67cab72021-12-02T14:40:50ZEstablishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts10.1038/s41467-020-19925-02041-1723https://doaj.org/article/181b7486d0ca47e2b97c7ebd8e67cab72020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19925-0https://doaj.org/toc/2041-1723Large population testing is a key step to controlling the COVID-19 pandemic. Here, the authors develop a targeted mass spectrometry system for peptide-based SARS-CoV-2 detection, allowing analysis of over 500 swab samples per day and enabling virus detection even after prolonged sample storage at room temperature.Karina Helena Morais CardozoAdriana LebkuchenGuilherme Gonçalves OkaiRodrigo Andrade SchuchLuciana Godoy VianaAline Nogueira OliveCarolina dos Santos LazariAna Maria FragaCelso Francisco Hernandes GranatoMaria Carolina Tostes PintãoValdemir Melechco CarvalhoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Karina Helena Morais Cardozo
Adriana Lebkuchen
Guilherme Gonçalves Okai
Rodrigo Andrade Schuch
Luciana Godoy Viana
Aline Nogueira Olive
Carolina dos Santos Lazari
Ana Maria Fraga
Celso Francisco Hernandes Granato
Maria Carolina Tostes Pintão
Valdemir Melechco Carvalho
Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts
description Large population testing is a key step to controlling the COVID-19 pandemic. Here, the authors develop a targeted mass spectrometry system for peptide-based SARS-CoV-2 detection, allowing analysis of over 500 swab samples per day and enabling virus detection even after prolonged sample storage at room temperature.
format article
author Karina Helena Morais Cardozo
Adriana Lebkuchen
Guilherme Gonçalves Okai
Rodrigo Andrade Schuch
Luciana Godoy Viana
Aline Nogueira Olive
Carolina dos Santos Lazari
Ana Maria Fraga
Celso Francisco Hernandes Granato
Maria Carolina Tostes Pintão
Valdemir Melechco Carvalho
author_facet Karina Helena Morais Cardozo
Adriana Lebkuchen
Guilherme Gonçalves Okai
Rodrigo Andrade Schuch
Luciana Godoy Viana
Aline Nogueira Olive
Carolina dos Santos Lazari
Ana Maria Fraga
Celso Francisco Hernandes Granato
Maria Carolina Tostes Pintão
Valdemir Melechco Carvalho
author_sort Karina Helena Morais Cardozo
title Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts
title_short Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts
title_full Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts
title_fullStr Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts
title_full_unstemmed Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts
title_sort establishing a mass spectrometry-based system for rapid detection of sars-cov-2 in large clinical sample cohorts
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/181b7486d0ca47e2b97c7ebd8e67cab7
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