Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine

We report the case of a 37-year-old woman (phototype II) who presented at our outpatient clinic with a two-month history of hyperpigmented plantar macules. Medical history revealed that the patient had taken capecitabine in the past three months as adjuvant chemotherapy for recurrent breast cancer....

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Autores principales:	Linda Tognetti, Michele Fimiani, Pietro Rubegni
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2015
Materias:	dermoscopy capecitabine plantar hyperpigmentation Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/181ce5a7d7eb4434893376ef122e2464
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spelling	oai:doaj.org-article:181ce5a7d7eb4434893376ef122e24642021-11-17T08:31:42ZBenign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine10.5826/dpc.0502a142160-9381https://doaj.org/article/181ce5a7d7eb4434893376ef122e24642015-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/761https://doaj.org/toc/2160-9381 We report the case of a 37-year-old woman (phototype II) who presented at our outpatient clinic with a two-month history of hyperpigmented plantar macules. Medical history revealed that the patient had taken capecitabine in the past three months as adjuvant chemotherapy for recurrent breast cancer. Dermoscopic examination of the plantar macules showed parallel ridge pattern with pigmentation in the furrows without obliteration of eccrine gland apertures. Besides in acral melanoma, parallel ridge pattern can also be observed in benign plantar lesions, such as congenital or acquired acral nevi, subcorneal hemorrhage, dye-related pigmentation and drug-induced hyperpigmentation, especially in patients with phototypes III-VI. The few reported cases of capecitabine-induced hyperpigmentation have been associated with hand and foot syndrome in patients with phototypes IV-V and palmar as well as plantar involvement. Linda TognettiMichele FimianiPietro RubegniMattioli1885articledermoscopycapecitabineplantarhyperpigmentationDermatologyRL1-803ENDermatology Practical & Conceptual (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	dermoscopy capecitabine plantar hyperpigmentation Dermatology RL1-803
spellingShingle	dermoscopy capecitabine plantar hyperpigmentation Dermatology RL1-803 Linda Tognetti Michele Fimiani Pietro Rubegni Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine
description	We report the case of a 37-year-old woman (phototype II) who presented at our outpatient clinic with a two-month history of hyperpigmented plantar macules. Medical history revealed that the patient had taken capecitabine in the past three months as adjuvant chemotherapy for recurrent breast cancer. Dermoscopic examination of the plantar macules showed parallel ridge pattern with pigmentation in the furrows without obliteration of eccrine gland apertures. Besides in acral melanoma, parallel ridge pattern can also be observed in benign plantar lesions, such as congenital or acquired acral nevi, subcorneal hemorrhage, dye-related pigmentation and drug-induced hyperpigmentation, especially in patients with phototypes III-VI. The few reported cases of capecitabine-induced hyperpigmentation have been associated with hand and foot syndrome in patients with phototypes IV-V and palmar as well as plantar involvement.
format	article
author	Linda Tognetti Michele Fimiani Pietro Rubegni
author_facet	Linda Tognetti Michele Fimiani Pietro Rubegni
author_sort	Linda Tognetti
title	Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine
title_short	Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine
title_full	Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine
title_fullStr	Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine
title_full_unstemmed	Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine
title_sort	benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine
publisher	Mattioli1885
publishDate	2015
url	https://doaj.org/article/181ce5a7d7eb4434893376ef122e2464
work_keys_str_mv	AT lindatognetti benigndermoscopicparallelridgepatterninplantarhyperpigmentationduetocapecitabine AT michelefimiani benigndermoscopicparallelridgepatterninplantarhyperpigmentationduetocapecitabine AT pietrorubegni benigndermoscopicparallelridgepatterninplantarhyperpigmentationduetocapecitabine
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Benign dermoscopic parallel ridge pattern in plantar hyperpigmentation due to capecitabine

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