Bioreducible liposomes for gene delivery: from the formulation to the mechanism of action.

Bioreducible liposomes for gene delivery: from the formulation to the mechanism of action.

<h4>Background</h4>A promising strategy to create stimuli-responsive gene delivery systems is to exploit the redox gradient between the oxidizing extracellular milieu and the reducing cytoplasm in order to disassemble DNA/cationic lipid complexes (lipoplexes). On these premises, we previ...

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Autores principales: Gabriele Candiani, Daniele Pezzoli, Laura Ciani, Roberto Chiesa, Sandra Ristori
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/1822ed1315c84a7192657baf8793dfe4
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