COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types

Immune cells are important in the pathogenesis of COVID-19. Here the authors assessed the effects of COVID-19-risk variants on gene expression in a range of immune cell types, highlighting their potential to impact the function of diverse immune cell types and influence severe disease.

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Autores principales:	Benjamin J. Schmiedel, Job Rocha, Cristian Gonzalez-Colin, Sourya Bhattacharyya, Ariel Madrigal, Christian H. Ottensmeier, Ferhat Ay, Vivek Chandra, Pandurangan Vijayanand
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1849316b872d4746b6e5d01562162e4d
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spelling	oai:doaj.org-article:1849316b872d4746b6e5d01562162e4d2021-11-21T12:35:01ZCOVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types10.1038/s41467-021-26888-32041-1723https://doaj.org/article/1849316b872d4746b6e5d01562162e4d2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26888-3https://doaj.org/toc/2041-1723Immune cells are important in the pathogenesis of COVID-19. Here the authors assessed the effects of COVID-19-risk variants on gene expression in a range of immune cell types, highlighting their potential to impact the function of diverse immune cell types and influence severe disease.Benjamin J. SchmiedelJob RochaCristian Gonzalez-ColinSourya BhattacharyyaAriel MadrigalChristian H. OttensmeierFerhat AyVivek ChandraPandurangan VijayanandNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benjamin J. Schmiedel Job Rocha Cristian Gonzalez-Colin Sourya Bhattacharyya Ariel Madrigal Christian H. Ottensmeier Ferhat Ay Vivek Chandra Pandurangan Vijayanand COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
description	Immune cells are important in the pathogenesis of COVID-19. Here the authors assessed the effects of COVID-19-risk variants on gene expression in a range of immune cell types, highlighting their potential to impact the function of diverse immune cell types and influence severe disease.
format	article
author	Benjamin J. Schmiedel Job Rocha Cristian Gonzalez-Colin Sourya Bhattacharyya Ariel Madrigal Christian H. Ottensmeier Ferhat Ay Vivek Chandra Pandurangan Vijayanand
author_facet	Benjamin J. Schmiedel Job Rocha Cristian Gonzalez-Colin Sourya Bhattacharyya Ariel Madrigal Christian H. Ottensmeier Ferhat Ay Vivek Chandra Pandurangan Vijayanand
author_sort	Benjamin J. Schmiedel
title	COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
title_short	COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
title_full	COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
title_fullStr	COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
title_full_unstemmed	COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
title_sort	covid-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1849316b872d4746b6e5d01562162e4d
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COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types

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