CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT

Epithelial-to-mesenchymal transition is a key process in tumorigenesis but little is known about the molecular mechanism regulating such process at the translational level. Here, the authors identify a subset of mRNAs important for this process that are specifically modulated by the RNA-binding prot...

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Autores principales: Arindam Chaudhury, Shebna Cheema, Joseph M. Fachini, Natee Kongchan, Guojun Lu, Lukas M. Simon, Tao Wang, Sufeng Mao, Daniel G. Rosen, Michael M. Ittmann, Susan G. Hilsenbeck, Chad A. Shaw, Joel R. Neilson
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/184a2be1bc5d42b7a1899779ab2debb3
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spelling oai:doaj.org-article:184a2be1bc5d42b7a1899779ab2debb32021-12-02T14:38:34ZCELF1 is a central node in post-transcriptional regulatory programmes underlying EMT10.1038/ncomms133622041-1723https://doaj.org/article/184a2be1bc5d42b7a1899779ab2debb32016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13362https://doaj.org/toc/2041-1723Epithelial-to-mesenchymal transition is a key process in tumorigenesis but little is known about the molecular mechanism regulating such process at the translational level. Here, the authors identify a subset of mRNAs important for this process that are specifically modulated by the RNA-binding protein CELF1.Arindam ChaudhuryShebna CheemaJoseph M. FachiniNatee KongchanGuojun LuLukas M. SimonTao WangSufeng MaoDaniel G. RosenMichael M. IttmannSusan G. HilsenbeckChad A. ShawJoel R. NeilsonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Arindam Chaudhury
Shebna Cheema
Joseph M. Fachini
Natee Kongchan
Guojun Lu
Lukas M. Simon
Tao Wang
Sufeng Mao
Daniel G. Rosen
Michael M. Ittmann
Susan G. Hilsenbeck
Chad A. Shaw
Joel R. Neilson
CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
description Epithelial-to-mesenchymal transition is a key process in tumorigenesis but little is known about the molecular mechanism regulating such process at the translational level. Here, the authors identify a subset of mRNAs important for this process that are specifically modulated by the RNA-binding protein CELF1.
format article
author Arindam Chaudhury
Shebna Cheema
Joseph M. Fachini
Natee Kongchan
Guojun Lu
Lukas M. Simon
Tao Wang
Sufeng Mao
Daniel G. Rosen
Michael M. Ittmann
Susan G. Hilsenbeck
Chad A. Shaw
Joel R. Neilson
author_facet Arindam Chaudhury
Shebna Cheema
Joseph M. Fachini
Natee Kongchan
Guojun Lu
Lukas M. Simon
Tao Wang
Sufeng Mao
Daniel G. Rosen
Michael M. Ittmann
Susan G. Hilsenbeck
Chad A. Shaw
Joel R. Neilson
author_sort Arindam Chaudhury
title CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
title_short CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
title_full CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
title_fullStr CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
title_full_unstemmed CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
title_sort celf1 is a central node in post-transcriptional regulatory programmes underlying emt
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/184a2be1bc5d42b7a1899779ab2debb3
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