SLAMF7 and IL-6R define distinct cytotoxic versus helper memory CD8+ T cells

We classically consider the T cell compartment divided into cytotoxic CD8+ T cells and multiple, different helper CD4+ T cell subsets. Here the authors demonstrate that distinct memory CD8+ T cell subsets phenotypically inhabit CD4+ T cell like populations including some with helper-like characteris...

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Auteurs principaux: Lucie Loyal, Sarah Warth, Karsten Jürchott, Felix Mölder, Christos Nikolaou, Nina Babel, Mikalai Nienen, Sibel Durlanik, Regina Stark, Beate Kruse, Marco Frentsch, Robert Sabat, Kerstin Wolk, Andreas Thiel
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/184c09f50a804df2b61297b698dfcd0d
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Résumé:We classically consider the T cell compartment divided into cytotoxic CD8+ T cells and multiple, different helper CD4+ T cell subsets. Here the authors demonstrate that distinct memory CD8+ T cell subsets phenotypically inhabit CD4+ T cell like populations including some with helper-like characteristics.