Novel treatments for osteoarthritis: a recent update

Yong Wu,1,* En Lin Goh,2,* Dong Wang,3 Shaocheng Ma3 1Leicester Medical School, University of Leicester, Leicester, UK; 2Faculty of Medicine, Imperial College London, London, UK; 3Biomechanics Research Group, Imperial College London, London, UK *These authors contributed equally to this work Abstrac...

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Autores principales:	Wu Y, Goh EL, Wang D, Ma S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Osteoarthritis novel treatment future therapy review Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/18631992bd6945f3b19855b4a20037ee
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spelling	oai:doaj.org-article:18631992bd6945f3b19855b4a20037ee2021-12-02T05:57:01ZNovel treatments for osteoarthritis: a recent update1179-156Xhttps://doaj.org/article/18631992bd6945f3b19855b4a20037ee2018-10-01T00:00:00Zhttps://www.dovepress.com/novel-treatments-for-osteoarthritis-a-recent-update-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XYong Wu,1,* En Lin Goh,2,* Dong Wang,3 Shaocheng Ma3 1Leicester Medical School, University of Leicester, Leicester, UK; 2Faculty of Medicine, Imperial College London, London, UK; 3Biomechanics Research Group, Imperial College London, London, UK *These authors contributed equally to this work Abstract: Osteoarthritis is the most prevalent chronic joint condition worldwide. The principles of osteoarthritis treatment are to alleviate pain and stiffness as well as maintain function, with current consensus guidelines recommending the use of a combination of conservative measures including physical therapy, analgesia, and surgical interventions such as arthroplasty. In recent years, several pharmacological therapies have emerged as potential alternatives. Although a disease-modifying osteoarthritis drug has yet to be identified, promising results have been reported in recent trials especially with serotonin–norepinephrine reuptake inhibitors, IL-1 antagonists, and antibodies to nerve growth factor. The present review aims to summarize and discuss the latest results of novel treatments for osteoarthritis and potential targets for future research. Keywords: osteoarthritis, novel treatment, future therapy, reviewWu YGoh ELWang DMa SDove Medical PressarticleOsteoarthritisnovel treatmentfuture therapyreviewDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 10, Pp 135-140 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Osteoarthritis novel treatment future therapy review Diseases of the musculoskeletal system RC925-935
spellingShingle	Osteoarthritis novel treatment future therapy review Diseases of the musculoskeletal system RC925-935 Wu Y Goh EL Wang D Ma S Novel treatments for osteoarthritis: a recent update
description	Yong Wu,1,* En Lin Goh,2,* Dong Wang,3 Shaocheng Ma3 1Leicester Medical School, University of Leicester, Leicester, UK; 2Faculty of Medicine, Imperial College London, London, UK; 3Biomechanics Research Group, Imperial College London, London, UK *These authors contributed equally to this work Abstract: Osteoarthritis is the most prevalent chronic joint condition worldwide. The principles of osteoarthritis treatment are to alleviate pain and stiffness as well as maintain function, with current consensus guidelines recommending the use of a combination of conservative measures including physical therapy, analgesia, and surgical interventions such as arthroplasty. In recent years, several pharmacological therapies have emerged as potential alternatives. Although a disease-modifying osteoarthritis drug has yet to be identified, promising results have been reported in recent trials especially with serotonin–norepinephrine reuptake inhibitors, IL-1 antagonists, and antibodies to nerve growth factor. The present review aims to summarize and discuss the latest results of novel treatments for osteoarthritis and potential targets for future research. Keywords: osteoarthritis, novel treatment, future therapy, review
format	article
author	Wu Y Goh EL Wang D Ma S
author_facet	Wu Y Goh EL Wang D Ma S
author_sort	Wu Y
title	Novel treatments for osteoarthritis: a recent update
title_short	Novel treatments for osteoarthritis: a recent update
title_full	Novel treatments for osteoarthritis: a recent update
title_fullStr	Novel treatments for osteoarthritis: a recent update
title_full_unstemmed	Novel treatments for osteoarthritis: a recent update
title_sort	novel treatments for osteoarthritis: a recent update
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/18631992bd6945f3b19855b4a20037ee
work_keys_str_mv	AT wuy noveltreatmentsforosteoarthritisarecentupdate AT gohel noveltreatmentsforosteoarthritisarecentupdate AT wangd noveltreatmentsforosteoarthritisarecentupdate AT mas noveltreatmentsforosteoarthritisarecentupdate
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Novel treatments for osteoarthritis: a recent update

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