The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer
Despite some well-characterized functions in cancer, the impact of most long non-coding RNAs remains unknown. Here, the authors discover the lncRNA lincNMR which is upregulated in cancer and drives cell proliferation by interacting with YBX1 and controlling nucleotide metabolism.
Guardado en:
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2020
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/186c4d276d704b2c8e6ccb57bb201c3b |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:186c4d276d704b2c8e6ccb57bb201c3b |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:186c4d276d704b2c8e6ccb57bb201c3b2021-12-02T18:02:51ZThe lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer10.1038/s41467-020-17007-92041-1723https://doaj.org/article/186c4d276d704b2c8e6ccb57bb201c3b2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17007-9https://doaj.org/toc/2041-1723Despite some well-characterized functions in cancer, the impact of most long non-coding RNAs remains unknown. Here, the authors discover the lncRNA lincNMR which is upregulated in cancer and drives cell proliferation by interacting with YBX1 and controlling nucleotide metabolism.Minakshi GandhiMatthias GroßJessica M. HollerSi’Ana A. CogginsNitin PatilJoerg H. LeupoldMathias MunschauerMonica SchenoneChristina R. HartiganHeike AllgayerBaek KimSven DiederichsNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Minakshi Gandhi Matthias Groß Jessica M. Holler Si’Ana A. Coggins Nitin Patil Joerg H. Leupold Mathias Munschauer Monica Schenone Christina R. Hartigan Heike Allgayer Baek Kim Sven Diederichs The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer |
| description |
Despite some well-characterized functions in cancer, the impact of most long non-coding RNAs remains unknown. Here, the authors discover the lncRNA lincNMR which is upregulated in cancer and drives cell proliferation by interacting with YBX1 and controlling nucleotide metabolism. |
| format |
article |
| author |
Minakshi Gandhi Matthias Groß Jessica M. Holler Si’Ana A. Coggins Nitin Patil Joerg H. Leupold Mathias Munschauer Monica Schenone Christina R. Hartigan Heike Allgayer Baek Kim Sven Diederichs |
| author_facet |
Minakshi Gandhi Matthias Groß Jessica M. Holler Si’Ana A. Coggins Nitin Patil Joerg H. Leupold Mathias Munschauer Monica Schenone Christina R. Hartigan Heike Allgayer Baek Kim Sven Diederichs |
| author_sort |
Minakshi Gandhi |
| title |
The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer |
| title_short |
The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer |
| title_full |
The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer |
| title_fullStr |
The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer |
| title_full_unstemmed |
The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer |
| title_sort |
lncrna lincnmr regulates nucleotide metabolism via a ybx1 - rrm2 axis in cancer |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/186c4d276d704b2c8e6ccb57bb201c3b |
| work_keys_str_mv |
AT minakshigandhi thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT matthiasgroß thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT jessicamholler thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT sianaacoggins thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT nitinpatil thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT joerghleupold thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT mathiasmunschauer thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT monicaschenone thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT christinarhartigan thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT heikeallgayer thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT baekkim thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT svendiederichs thelncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT minakshigandhi lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT matthiasgroß lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT jessicamholler lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT sianaacoggins lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT nitinpatil lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT joerghleupold lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT mathiasmunschauer lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT monicaschenone lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT christinarhartigan lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT heikeallgayer lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT baekkim lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer AT svendiederichs lncrnalincnmrregulatesnucleotidemetabolismviaaybx1rrm2axisincancer |
| _version_ |
1718378853607407616 |