The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer

Despite some well-characterized functions in cancer, the impact of most long non-coding RNAs remains unknown. Here, the authors discover the lncRNA lincNMR which is upregulated in cancer and drives cell proliferation by interacting with YBX1 and controlling nucleotide metabolism.

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Bibliographic Details
Main Authors: Minakshi Gandhi, Matthias Groß, Jessica M. Holler, Si’Ana A. Coggins, Nitin Patil, Joerg H. Leupold, Mathias Munschauer, Monica Schenone, Christina R. Hartigan, Heike Allgayer, Baek Kim, Sven Diederichs
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/186c4d276d704b2c8e6ccb57bb201c3b
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