A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function

The current hemostasis assays are unable to predict thrombotic or bleeding risk in clinics. Here, Jain et al. present a novel microfluidic device mimicking stenosed arterioles that determines clotting times in vitroand in extracorporeal circuits, offering a simple and reliable monitoring of blood ho...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Abhishek Jain, Amanda Graveline, Anna Waterhouse, Andyna Vernet, Robert Flaumenhaft, Donald E. Ingber
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/1870ac5f942040eb82300f0b7469baf4
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:1870ac5f942040eb82300f0b7469baf4
record_format dspace
spelling oai:doaj.org-article:1870ac5f942040eb82300f0b7469baf42021-12-02T14:38:35ZA shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function10.1038/ncomms101762041-1723https://doaj.org/article/1870ac5f942040eb82300f0b7469baf42016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10176https://doaj.org/toc/2041-1723The current hemostasis assays are unable to predict thrombotic or bleeding risk in clinics. Here, Jain et al. present a novel microfluidic device mimicking stenosed arterioles that determines clotting times in vitroand in extracorporeal circuits, offering a simple and reliable monitoring of blood homeostasis and platelet function.Abhishek JainAmanda GravelineAnna WaterhouseAndyna VernetRobert FlaumenhaftDonald E. IngberNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Abhishek Jain
Amanda Graveline
Anna Waterhouse
Andyna Vernet
Robert Flaumenhaft
Donald E. Ingber
A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
description The current hemostasis assays are unable to predict thrombotic or bleeding risk in clinics. Here, Jain et al. present a novel microfluidic device mimicking stenosed arterioles that determines clotting times in vitroand in extracorporeal circuits, offering a simple and reliable monitoring of blood homeostasis and platelet function.
format article
author Abhishek Jain
Amanda Graveline
Anna Waterhouse
Andyna Vernet
Robert Flaumenhaft
Donald E. Ingber
author_facet Abhishek Jain
Amanda Graveline
Anna Waterhouse
Andyna Vernet
Robert Flaumenhaft
Donald E. Ingber
author_sort Abhishek Jain
title A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
title_short A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
title_full A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
title_fullStr A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
title_full_unstemmed A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
title_sort shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/1870ac5f942040eb82300f0b7469baf4
work_keys_str_mv AT abhishekjain asheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT amandagraveline asheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT annawaterhouse asheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT andynavernet asheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT robertflaumenhaft asheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT donaldeingber asheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT abhishekjain sheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT amandagraveline sheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT annawaterhouse sheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT andynavernet sheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT robertflaumenhaft sheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
AT donaldeingber sheargradientactivatedmicrofluidicdeviceforautomatedmonitoringofwholebloodhaemostasisandplateletfunction
_version_ 1718390936501747712