A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function
The current hemostasis assays are unable to predict thrombotic or bleeding risk in clinics. Here, Jain et al. present a novel microfluidic device mimicking stenosed arterioles that determines clotting times in vitroand in extracorporeal circuits, offering a simple and reliable monitoring of blood ho...
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Nature Portfolio
2016
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oai:doaj.org-article:1870ac5f942040eb82300f0b7469baf42021-12-02T14:38:35ZA shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function10.1038/ncomms101762041-1723https://doaj.org/article/1870ac5f942040eb82300f0b7469baf42016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10176https://doaj.org/toc/2041-1723The current hemostasis assays are unable to predict thrombotic or bleeding risk in clinics. Here, Jain et al. present a novel microfluidic device mimicking stenosed arterioles that determines clotting times in vitroand in extracorporeal circuits, offering a simple and reliable monitoring of blood homeostasis and platelet function.Abhishek JainAmanda GravelineAnna WaterhouseAndyna VernetRobert FlaumenhaftDonald E. IngberNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
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Science Q Abhishek Jain Amanda Graveline Anna Waterhouse Andyna Vernet Robert Flaumenhaft Donald E. Ingber A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function |
description |
The current hemostasis assays are unable to predict thrombotic or bleeding risk in clinics. Here, Jain et al. present a novel microfluidic device mimicking stenosed arterioles that determines clotting times in vitroand in extracorporeal circuits, offering a simple and reliable monitoring of blood homeostasis and platelet function. |
format |
article |
author |
Abhishek Jain Amanda Graveline Anna Waterhouse Andyna Vernet Robert Flaumenhaft Donald E. Ingber |
author_facet |
Abhishek Jain Amanda Graveline Anna Waterhouse Andyna Vernet Robert Flaumenhaft Donald E. Ingber |
author_sort |
Abhishek Jain |
title |
A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function |
title_short |
A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function |
title_full |
A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function |
title_fullStr |
A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function |
title_full_unstemmed |
A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function |
title_sort |
shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/1870ac5f942040eb82300f0b7469baf4 |
work_keys_str_mv |
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