A BAFF/APRIL axis regulates obesogenic diet-driven weight gain
Interactions between the immune system and adipose tissue contribute to the regulation of body weight, however, the underlying mechanisms remain incompletely understood. Here the authors dissect the role of two structurally and functionally similar immune mediators, BAFF and APRIL, in modifying diet...
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Nature Portfolio
2021
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oai:doaj.org-article:1874a0fdf3df440c914731f67be8205d2021-12-02T14:58:51ZA BAFF/APRIL axis regulates obesogenic diet-driven weight gain10.1038/s41467-021-23084-12041-1723https://doaj.org/article/1874a0fdf3df440c914731f67be8205d2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23084-1https://doaj.org/toc/2041-1723Interactions between the immune system and adipose tissue contribute to the regulation of body weight, however, the underlying mechanisms remain incompletely understood. Here the authors dissect the role of two structurally and functionally similar immune mediators, BAFF and APRIL, in modifying diet-induced weight gain and adipocyte lipid handling.Calvin C. ChanIsaac T. W. HarleyPaul T. PflugerAurelien TrompetteTraci E. StankiewiczJessica L. AllenMaria E. Moreno-FernandezMichelle S. M. A. DamenJarren R. OatesPablo C. AlarconJessica R. DollMatthew J. FlickLeah M. FlickJoan Sanchez-GurmachesRajib MukherjeeRebekah KarnsMichael HelmrathThomas H. IngeStuart P. WeisbergSünje J. PampDavid A. RelmanRandy J. SeeleyMatthias H. TschöpChristopher L. KarpSenad DivanovicNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
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EN |
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Science Q |
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Science Q Calvin C. Chan Isaac T. W. Harley Paul T. Pfluger Aurelien Trompette Traci E. Stankiewicz Jessica L. Allen Maria E. Moreno-Fernandez Michelle S. M. A. Damen Jarren R. Oates Pablo C. Alarcon Jessica R. Doll Matthew J. Flick Leah M. Flick Joan Sanchez-Gurmaches Rajib Mukherjee Rebekah Karns Michael Helmrath Thomas H. Inge Stuart P. Weisberg Sünje J. Pamp David A. Relman Randy J. Seeley Matthias H. Tschöp Christopher L. Karp Senad Divanovic A BAFF/APRIL axis regulates obesogenic diet-driven weight gain |
| description |
Interactions between the immune system and adipose tissue contribute to the regulation of body weight, however, the underlying mechanisms remain incompletely understood. Here the authors dissect the role of two structurally and functionally similar immune mediators, BAFF and APRIL, in modifying diet-induced weight gain and adipocyte lipid handling. |
| format |
article |
| author |
Calvin C. Chan Isaac T. W. Harley Paul T. Pfluger Aurelien Trompette Traci E. Stankiewicz Jessica L. Allen Maria E. Moreno-Fernandez Michelle S. M. A. Damen Jarren R. Oates Pablo C. Alarcon Jessica R. Doll Matthew J. Flick Leah M. Flick Joan Sanchez-Gurmaches Rajib Mukherjee Rebekah Karns Michael Helmrath Thomas H. Inge Stuart P. Weisberg Sünje J. Pamp David A. Relman Randy J. Seeley Matthias H. Tschöp Christopher L. Karp Senad Divanovic |
| author_facet |
Calvin C. Chan Isaac T. W. Harley Paul T. Pfluger Aurelien Trompette Traci E. Stankiewicz Jessica L. Allen Maria E. Moreno-Fernandez Michelle S. M. A. Damen Jarren R. Oates Pablo C. Alarcon Jessica R. Doll Matthew J. Flick Leah M. Flick Joan Sanchez-Gurmaches Rajib Mukherjee Rebekah Karns Michael Helmrath Thomas H. Inge Stuart P. Weisberg Sünje J. Pamp David A. Relman Randy J. Seeley Matthias H. Tschöp Christopher L. Karp Senad Divanovic |
| author_sort |
Calvin C. Chan |
| title |
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain |
| title_short |
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain |
| title_full |
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain |
| title_fullStr |
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain |
| title_full_unstemmed |
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain |
| title_sort |
baff/april axis regulates obesogenic diet-driven weight gain |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/1874a0fdf3df440c914731f67be8205d |
| work_keys_str_mv |
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