A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells

A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells

Dynamic labeling and tracking of organelle–organelle contacts is essential to understand the formation and function of these interactions. Here the authors present a small molecule probe, Coupa, that labels mitochondria and lysosomes with blue and red fluorescence, respectively.

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Autores principales: Qixin Chen, Hongbao Fang, Xintian Shao, Zhiqi Tian, Shanshan Geng, Yuming Zhang, Huaxun Fan, Pan Xiang, Jie Zhang, Xiaohe Tian, Kai Zhang, Weijiang He, Zijian Guo, Jiajie Diao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
Q
Acceso en línea:https://doaj.org/article/1874dd6bf6214e2ba26b5f13d4206d54
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spelling oai:doaj.org-article:1874dd6bf6214e2ba26b5f13d4206d542021-12-02T14:16:47ZA dual-labeling probe to track functional mitochondria–lysosome interactions in live cells10.1038/s41467-020-20067-62041-1723https://doaj.org/article/1874dd6bf6214e2ba26b5f13d4206d542020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20067-6https://doaj.org/toc/2041-1723Dynamic labeling and tracking of organelle–organelle contacts is essential to understand the formation and function of these interactions. Here the authors present a small molecule probe, Coupa, that labels mitochondria and lysosomes with blue and red fluorescence, respectively.Qixin ChenHongbao FangXintian ShaoZhiqi TianShanshan GengYuming ZhangHuaxun FanPan XiangJie ZhangXiaohe TianKai ZhangWeijiang HeZijian GuoJiajie DiaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qixin Chen
Hongbao Fang
Xintian Shao
Zhiqi Tian
Shanshan Geng
Yuming Zhang
Huaxun Fan
Pan Xiang
Jie Zhang
Xiaohe Tian
Kai Zhang
Weijiang He
Zijian Guo
Jiajie Diao
A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
description Dynamic labeling and tracking of organelle–organelle contacts is essential to understand the formation and function of these interactions. Here the authors present a small molecule probe, Coupa, that labels mitochondria and lysosomes with blue and red fluorescence, respectively.
format article
author Qixin Chen
Hongbao Fang
Xintian Shao
Zhiqi Tian
Shanshan Geng
Yuming Zhang
Huaxun Fan
Pan Xiang
Jie Zhang
Xiaohe Tian
Kai Zhang
Weijiang He
Zijian Guo
Jiajie Diao
author_facet Qixin Chen
Hongbao Fang
Xintian Shao
Zhiqi Tian
Shanshan Geng
Yuming Zhang
Huaxun Fan
Pan Xiang
Jie Zhang
Xiaohe Tian
Kai Zhang
Weijiang He
Zijian Guo
Jiajie Diao
author_sort Qixin Chen
title A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
title_short A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
title_full A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
title_fullStr A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
title_full_unstemmed A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
title_sort dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/1874dd6bf6214e2ba26b5f13d4206d54
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