A dual-labeling probe to track functional mitochondria–lysosome interactions in live cells
Dynamic labeling and tracking of organelle–organelle contacts is essential to understand the formation and function of these interactions. Here the authors present a small molecule probe, Coupa, that labels mitochondria and lysosomes with blue and red fluorescence, respectively.
Guardado en:
Autores principales: | Qixin Chen, Hongbao Fang, Xintian Shao, Zhiqi Tian, Shanshan Geng, Yuming Zhang, Huaxun Fan, Pan Xiang, Jie Zhang, Xiaohe Tian, Kai Zhang, Weijiang He, Zijian Guo, Jiajie Diao |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1874dd6bf6214e2ba26b5f13d4206d54 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Simultaneous Zn2+ tracking in multiple organelles using super-resolution morphology-correlated organelle identification in living cells
por: Hongbao Fang, et al.
Publicado: (2021) -
Tracking the formation and degradation of fatty-acid-accumulated mitochondria using label-free chemical imaging
por: Chi Zhang, et al.
Publicado: (2021) -
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
por: Yuming Zhang, et al.
Publicado: (2021) -
Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
por: Rhianna C. Laker, et al.
Publicado: (2017) -
Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease
por: Soojin Kim, et al.
Publicado: (2021)