Delivery of the gene encoding the tumor suppressor Sef into prostate tumors by therapeutic-ultrasound inhibits both tumor angiogenesis and growth

Abstract Carcinomas constitute over 80% of all human cancer types with no effective therapy for metastatic disease. Here, we demonstrate, for the first time, the efficacy of therapeutic-ultrasound (TUS) to deliver a human tumor suppressor gene, hSef-b, to prostate tumors in vivo. Sef is downregulate...

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Autores principales: Sabrin Mishel, Boris Shneyer, Lina Korsensky, Orit Goldshmidt-Tran, Tom Haber, Marcelle Machluf, Dina Ron
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/18777b20c254425b9579b5a09b321728
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