The functional and structural characteristics of the emotion network in alexithymia

Dai Han,1–3 Mei Li,4 Minjun Mei,4 Xiaofei Sun4 1Institutes of Psychological Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China; 2Children and Adolescents Mental Health Joint Clinic, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China; 3Zhejiang Ke...

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Autores principales:	Han D, Li M, Mei MJ, Sun XF
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	emotion network rsfMRI VBM functional connectivity structural connectivity Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/187f1fd1ed7c4a3da8536db6ee0312af
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spelling	oai:doaj.org-article:187f1fd1ed7c4a3da8536db6ee0312af2021-12-02T02:29:13ZThe functional and structural characteristics of the emotion network in alexithymia1178-2021https://doaj.org/article/187f1fd1ed7c4a3da8536db6ee0312af2018-04-01T00:00:00Zhttps://www.dovepress.com/the-functional-and-structural-characteristics-of-the-emotion-network-i-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Dai Han,1–3 Mei Li,4 Minjun Mei,4 Xiaofei Sun4 1Institutes of Psychological Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China; 2Children and Adolescents Mental Health Joint Clinic, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China; 3Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, Zhejiang, China; 4Mental Health Education and Counseling Center, Hangzhou Normal University, Hangzhou, Zhejiang, China Background: Alexithymia is a multifaceted personality trait characterized by emotional dysfunction.Methods: In this study, the functional and structural features of the emotion network in alexithymia were investigated using resting-state functional MRI (rsfMRI), voxel-based morphometry (VBM), functional connectivity (FC) analysis, and diffusion tensor imaging (DTI). Alexithymic and non-alexithymic students were recruited from the local university. The intrinsic neural activity and gray matter density of the brain regions in the emotion network were measured using rsfMRI and VBM; the FC and structural connectivity of the brain regions in the emotion network were measured using FC analysis and DTI.Results: The altered intrinsic neural activity in V1, rostral dorsal anterior cingulate cortex, and left amygdala, and the weak FC between V1 and left superior temporal gyrus and V1 and left paracentral lobule in alexithymia subjects were identified. However, no alteration of the structure and structural connectivity of the emotion network was identified.Conclusion: The results indicated that the development of alexithymia might have been caused only by slight alteration of the neural activity. Furthermore, the results suggest that noninvasive treatment technologies for improving the brain activity are suitable for alexithymic individuals. Keywords: emotion network, rsfMRI, VBM, functional connectivity, structural connectivityHan DLi MMei MJSun XFDove Medical Pressarticleemotion networkrsfMRIVBMfunctional connectivitystructural connectivityNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 991-998 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	emotion network rsfMRI VBM functional connectivity structural connectivity Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	emotion network rsfMRI VBM functional connectivity structural connectivity Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Han D Li M Mei MJ Sun XF The functional and structural characteristics of the emotion network in alexithymia
description	Dai Han,1–3 Mei Li,4 Minjun Mei,4 Xiaofei Sun4 1Institutes of Psychological Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China; 2Children and Adolescents Mental Health Joint Clinic, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China; 3Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, Zhejiang, China; 4Mental Health Education and Counseling Center, Hangzhou Normal University, Hangzhou, Zhejiang, China Background: Alexithymia is a multifaceted personality trait characterized by emotional dysfunction.Methods: In this study, the functional and structural features of the emotion network in alexithymia were investigated using resting-state functional MRI (rsfMRI), voxel-based morphometry (VBM), functional connectivity (FC) analysis, and diffusion tensor imaging (DTI). Alexithymic and non-alexithymic students were recruited from the local university. The intrinsic neural activity and gray matter density of the brain regions in the emotion network were measured using rsfMRI and VBM; the FC and structural connectivity of the brain regions in the emotion network were measured using FC analysis and DTI.Results: The altered intrinsic neural activity in V1, rostral dorsal anterior cingulate cortex, and left amygdala, and the weak FC between V1 and left superior temporal gyrus and V1 and left paracentral lobule in alexithymia subjects were identified. However, no alteration of the structure and structural connectivity of the emotion network was identified.Conclusion: The results indicated that the development of alexithymia might have been caused only by slight alteration of the neural activity. Furthermore, the results suggest that noninvasive treatment technologies for improving the brain activity are suitable for alexithymic individuals. Keywords: emotion network, rsfMRI, VBM, functional connectivity, structural connectivity
format	article
author	Han D Li M Mei MJ Sun XF
author_facet	Han D Li M Mei MJ Sun XF
author_sort	Han D
title	The functional and structural characteristics of the emotion network in alexithymia
title_short	The functional and structural characteristics of the emotion network in alexithymia
title_full	The functional and structural characteristics of the emotion network in alexithymia
title_fullStr	The functional and structural characteristics of the emotion network in alexithymia
title_full_unstemmed	The functional and structural characteristics of the emotion network in alexithymia
title_sort	functional and structural characteristics of the emotion network in alexithymia
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/187f1fd1ed7c4a3da8536db6ee0312af
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_version_	1718402452108083200

The functional and structural characteristics of the emotion network in alexithymia

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