Autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case

Abstract Background Autoimmune polyendocrine syndrome, also called polyglandular autoimmune syndrome, is a rare immune‐mediated disorder that involves various endocrine glands. Purpose To report autoimmune polyendocrine syndrome in a dog. Methods A 9‐year‐old spayed female miniature poodle diagnosed...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Seo‐Young Hwang, Ju‐Hyun An, Jeong‐Hwa Lee, Su‐Min Park, Hyung Kyu Chae, Kyung‐Bo Kim, Woo‐Jin Song, Hwa‐Young Youn
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	glomerular nephropathy hyperadrenocorticism inflammatory bowel disease insulin‐dependent diabetes mellitus polyglandular autoimmune syndrome Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/18834aa147cb44a6b835549e16d76e2b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:18834aa147cb44a6b835549e16d76e2b
record_format	dspace
spelling	oai:doaj.org-article:18834aa147cb44a6b835549e16d76e2b2021-11-19T17:14:25ZAutoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case2053-109510.1002/vms3.625https://doaj.org/article/18834aa147cb44a6b835549e16d76e2b2021-11-01T00:00:00Zhttps://doi.org/10.1002/vms3.625https://doaj.org/toc/2053-1095Abstract Background Autoimmune polyendocrine syndrome, also called polyglandular autoimmune syndrome, is a rare immune‐mediated disorder that involves various endocrine glands. Purpose To report autoimmune polyendocrine syndrome in a dog. Methods A 9‐year‐old spayed female miniature poodle diagnosed with insulin‐dependent diabetes mellitus emergently visited our clinic for anorexia, severe depression, and vomiting. Hyponatremia, hypochloridemia, and recurrent hypoglycaemia were found. Hypoadrenocorticism was diagnosed based on consistent clinical signs and repeated adrenocorticotropic hormone stimulation tests. Results After injecting deoxycorticosterone pivalate and increasing the oral prednisolone dose, the patient's systemic condition improved. Conclusions To the best of our knowledge, this is the first case report of hypoadrenocorticism concurrent with diabetes mellitus in a dog. Furthermore, we would like to present the probability of an immune‐mediated disorder with multiple organs involved, like type IV autoimmune polyendocrine syndrome in humans.Seo‐Young HwangJu‐Hyun AnJeong‐Hwa LeeSu‐Min ParkHyung Kyu ChaeKyung‐Bo KimWoo‐Jin SongHwa‐Young YounWileyarticleglomerular nephropathyhyperadrenocorticisminflammatory bowel diseaseinsulin‐dependent diabetes mellituspolyglandular autoimmune syndromeVeterinary medicineSF600-1100ENVeterinary Medicine and Science, Vol 7, Iss 6, Pp 2120-2123 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	glomerular nephropathy hyperadrenocorticism inflammatory bowel disease insulin‐dependent diabetes mellitus polyglandular autoimmune syndrome Veterinary medicine SF600-1100
spellingShingle	glomerular nephropathy hyperadrenocorticism inflammatory bowel disease insulin‐dependent diabetes mellitus polyglandular autoimmune syndrome Veterinary medicine SF600-1100 Seo‐Young Hwang Ju‐Hyun An Jeong‐Hwa Lee Su‐Min Park Hyung Kyu Chae Kyung‐Bo Kim Woo‐Jin Song Hwa‐Young Youn Autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case
description	Abstract Background Autoimmune polyendocrine syndrome, also called polyglandular autoimmune syndrome, is a rare immune‐mediated disorder that involves various endocrine glands. Purpose To report autoimmune polyendocrine syndrome in a dog. Methods A 9‐year‐old spayed female miniature poodle diagnosed with insulin‐dependent diabetes mellitus emergently visited our clinic for anorexia, severe depression, and vomiting. Hyponatremia, hypochloridemia, and recurrent hypoglycaemia were found. Hypoadrenocorticism was diagnosed based on consistent clinical signs and repeated adrenocorticotropic hormone stimulation tests. Results After injecting deoxycorticosterone pivalate and increasing the oral prednisolone dose, the patient's systemic condition improved. Conclusions To the best of our knowledge, this is the first case report of hypoadrenocorticism concurrent with diabetes mellitus in a dog. Furthermore, we would like to present the probability of an immune‐mediated disorder with multiple organs involved, like type IV autoimmune polyendocrine syndrome in humans.
format	article
author	Seo‐Young Hwang Ju‐Hyun An Jeong‐Hwa Lee Su‐Min Park Hyung Kyu Chae Kyung‐Bo Kim Woo‐Jin Song Hwa‐Young Youn
author_facet	Seo‐Young Hwang Ju‐Hyun An Jeong‐Hwa Lee Su‐Min Park Hyung Kyu Chae Kyung‐Bo Kim Woo‐Jin Song Hwa‐Young Youn
author_sort	Seo‐Young Hwang
title	Autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case
title_short	Autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case
title_full	Autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case
title_fullStr	Autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case
title_full_unstemmed	Autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case
title_sort	autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: a rare case
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/18834aa147cb44a6b835549e16d76e2b
work_keys_str_mv	AT seoyounghwang autoimmunepolyendocrinesyndromewithhypoadrenocorticismanddiabetesmellitusinadogararecase AT juhyunan autoimmunepolyendocrinesyndromewithhypoadrenocorticismanddiabetesmellitusinadogararecase AT jeonghwalee autoimmunepolyendocrinesyndromewithhypoadrenocorticismanddiabetesmellitusinadogararecase AT suminpark autoimmunepolyendocrinesyndromewithhypoadrenocorticismanddiabetesmellitusinadogararecase AT hyungkyuchae autoimmunepolyendocrinesyndromewithhypoadrenocorticismanddiabetesmellitusinadogararecase AT kyungbokim autoimmunepolyendocrinesyndromewithhypoadrenocorticismanddiabetesmellitusinadogararecase AT woojinsong autoimmunepolyendocrinesyndromewithhypoadrenocorticismanddiabetesmellitusinadogararecase AT hwayoungyoun autoimmunepolyendocrinesyndromewithhypoadrenocorticismanddiabetesmellitusinadogararecase
_version_	1718419997150150656

Autoimmune polyendocrine syndrome with hypoadrenocorticism and diabetes mellitus in a dog: A rare case

Ejemplares similares