Incidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast Ethiopia

Objectives In order to maximise the prevention of hospital-acquired infections (HAIs) and antimicrobial resistance, data on the incidence of HAIs are crucial. In Ethiopia, data about the occurrence of HAIs among hospitalised paediatric patients are lacking. We aim to determine the incidence and risk...

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Autores principales:	Biniyam Sahiledengle, Fekadu Seyoum, Daniel Abebe, Eshetu Nigussie Geleta, Getahun Negash, Abdurhaman Kalu, Demelash Woldeyohannes, Yohannes Tekalegn, Demisu Zenbaba, Bruce John Edward Quisido
Formato:	article
Lenguaje:	EN
Publicado:	BMJ Publishing Group 2020
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/188a4d0ba59c48f9bf607ebefb84a971
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spelling	oai:doaj.org-article:188a4d0ba59c48f9bf607ebefb84a9712021-11-18T01:30:05ZIncidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast Ethiopia10.1136/bmjopen-2020-0379972044-6055https://doaj.org/article/188a4d0ba59c48f9bf607ebefb84a9712020-12-01T00:00:00Zhttps://bmjopen.bmj.com/content/10/12/e037997.fullhttps://doaj.org/toc/2044-6055Objectives In order to maximise the prevention of hospital-acquired infections (HAIs) and antimicrobial resistance, data on the incidence of HAIs are crucial. In Ethiopia, data about the occurrence of HAIs among hospitalised paediatric patients are lacking. We aim to determine the incidence and risk factors of HAIs among paediatric patients in Ethiopia.Design A prospective cohort study.Setting A teaching hospital in southeast Ethiopia.Participants 448 hospitalised paediatric patients admitted between 1 November 2018 and 30 June 2019.Primary and secondary outcome measures Incidence and risk factors of hospital-acquired infections.Results A total of 448 paediatric patients were followed for 3227 patient days. The median age of the patients was 8 months (IQR: 2–26 months). The incidence rate of HAIs was 17.7 per 1000 paediatric days of follow-up; while the overall cumulative incidence was 12.7% (95% CI 9.8% to 15.8%) over 8 months. Children who stayed greater than 6 days in the hospital (median day) (adjusted risk ratio (RR): 2.58, 95% CI 1.52 to 4.38), and children with underlying disease conditions of severe acute malnutrition (adjusted RR: 2.83, 95% CI 1.61 to 4.97) had higher risks of developing HAIs.Conclusions The overall cumulative incidence of HAIs was about 13 per 100 admitted children. Length of stay in the hospital and underlying conditions of severe acute malnutrition were found to be important factors associated with increased risk of HAIs.Biniyam SahiledengleFekadu SeyoumDaniel AbebeEshetu Nigussie GeletaGetahun NegashAbdurhaman KaluDemelash WoldeyohannesYohannes TekalegnDemisu ZenbabaBruce John Edward QuisidoBMJ Publishing GrouparticleMedicineRENBMJ Open, Vol 10, Iss 12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Biniyam Sahiledengle Fekadu Seyoum Daniel Abebe Eshetu Nigussie Geleta Getahun Negash Abdurhaman Kalu Demelash Woldeyohannes Yohannes Tekalegn Demisu Zenbaba Bruce John Edward Quisido Incidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast Ethiopia
description	Objectives In order to maximise the prevention of hospital-acquired infections (HAIs) and antimicrobial resistance, data on the incidence of HAIs are crucial. In Ethiopia, data about the occurrence of HAIs among hospitalised paediatric patients are lacking. We aim to determine the incidence and risk factors of HAIs among paediatric patients in Ethiopia.Design A prospective cohort study.Setting A teaching hospital in southeast Ethiopia.Participants 448 hospitalised paediatric patients admitted between 1 November 2018 and 30 June 2019.Primary and secondary outcome measures Incidence and risk factors of hospital-acquired infections.Results A total of 448 paediatric patients were followed for 3227 patient days. The median age of the patients was 8 months (IQR: 2–26 months). The incidence rate of HAIs was 17.7 per 1000 paediatric days of follow-up; while the overall cumulative incidence was 12.7% (95% CI 9.8% to 15.8%) over 8 months. Children who stayed greater than 6 days in the hospital (median day) (adjusted risk ratio (RR): 2.58, 95% CI 1.52 to 4.38), and children with underlying disease conditions of severe acute malnutrition (adjusted RR: 2.83, 95% CI 1.61 to 4.97) had higher risks of developing HAIs.Conclusions The overall cumulative incidence of HAIs was about 13 per 100 admitted children. Length of stay in the hospital and underlying conditions of severe acute malnutrition were found to be important factors associated with increased risk of HAIs.
format	article
author	Biniyam Sahiledengle Fekadu Seyoum Daniel Abebe Eshetu Nigussie Geleta Getahun Negash Abdurhaman Kalu Demelash Woldeyohannes Yohannes Tekalegn Demisu Zenbaba Bruce John Edward Quisido
author_facet	Biniyam Sahiledengle Fekadu Seyoum Daniel Abebe Eshetu Nigussie Geleta Getahun Negash Abdurhaman Kalu Demelash Woldeyohannes Yohannes Tekalegn Demisu Zenbaba Bruce John Edward Quisido
author_sort	Biniyam Sahiledengle
title	Incidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast Ethiopia
title_short	Incidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast Ethiopia
title_full	Incidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast Ethiopia
title_fullStr	Incidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast Ethiopia
title_full_unstemmed	Incidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast Ethiopia
title_sort	incidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast ethiopia
publisher	BMJ Publishing Group
publishDate	2020
url	https://doaj.org/article/188a4d0ba59c48f9bf607ebefb84a971
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Incidence and risk factors for hospital-acquired infection among paediatric patients in a teaching hospital: a prospective study in southeast Ethiopia

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