Whole-cell imaging of plasma membrane receptors by 3D lattice light-sheet dSTORM

The organisation of plasma membrane receptors is important for their function. Here the authors combine lattice light-sheet microscopy with 3D single-molecule localisation microscopy (dSTORM) and single-particle tracking to study the distribution and motility of several surface receptors.

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Detalles Bibliográficos
Autores principales: Felix Wäldchen, Jan Schlegel, Ralph Götz, Michael Luciano, Martin Schnermann, Sören Doose, Markus Sauer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/18957698184b45c0aa8c46e9638ed9b3
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Descripción
Sumario:The organisation of plasma membrane receptors is important for their function. Here the authors combine lattice light-sheet microscopy with 3D single-molecule localisation microscopy (dSTORM) and single-particle tracking to study the distribution and motility of several surface receptors.