Potentiating antibiotic efficacy via perturbation of non-essential gene expression

Otoupal et al. use a systematic approach to investigate the effects of fitness neutral gene perturbations and antibiotic synergy in Escherichia coli. These neutral fitness interactions worked as co-therapies in a Salmonella enterica infection and informed the design of re-sensitization therapies in...

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Autores principales: Peter B. Otoupal, Kristen A. Eller, Keesha E. Erickson, Jocelyn Campos, Thomas R. Aunins, Anushree Chatterjee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1897d57a87004ebaa77d9c5fc86ebd05
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