Non-canonical activation of OmpR drives acid and osmotic stress responses in single bacterial cells

OmpR is a transcription factor activated in acid and osmotic responses of Gram-negative bacteria, leading to acidification of the bacterial cytoplasm. Here the authors use single cell pH imaging to define the role of OmpR-regulated genes in the acidification response to osmotic and acid stress of Sa...

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Autores principales: Smarajit Chakraborty, Ricksen S. Winardhi, Leslie K. Morgan, Jie Yan, Linda J. Kenney
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/189cfa10e5dc4b49a66243af61ebc845
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Sumario:OmpR is a transcription factor activated in acid and osmotic responses of Gram-negative bacteria, leading to acidification of the bacterial cytoplasm. Here the authors use single cell pH imaging to define the role of OmpR-regulated genes in the acidification response to osmotic and acid stress of Salmonella and E. coli.