Comprehensive analysis of single cell ATAC-seq data with SnapATAC

Comprehensive analysis of single cell ATAC-seq data with SnapATAC

Single cell analysis of transposase-accessible chromatin is deepening our understanding on the origins of cellular diversity, yet methods are limited by data sparsity. Here, the authors introduce SnapATAC, a pipeline to resolve cellular heterogeneity and reveal candidate regulatory elements across d...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Rongxin Fang, Sebastian Preissl, Yang Li, Xiaomeng Hou, Jacinta Lucero, Xinxin Wang, Amir Motamedi, Andrew K. Shiau, Xinzhu Zhou, Fangming Xie, Eran A. Mukamel, Kai Zhang, Yanxiao Zhang, M. Margarita Behrens, Joseph R. Ecker, Bing Ren
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/18a2c5f660e04078a2e5f322063c59a2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:18a2c5f660e04078a2e5f322063c59a2
record_format dspace
spelling oai:doaj.org-article:18a2c5f660e04078a2e5f322063c59a22021-12-02T13:14:59ZComprehensive analysis of single cell ATAC-seq data with SnapATAC10.1038/s41467-021-21583-92041-1723https://doaj.org/article/18a2c5f660e04078a2e5f322063c59a22021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21583-9https://doaj.org/toc/2041-1723Single cell analysis of transposase-accessible chromatin is deepening our understanding on the origins of cellular diversity, yet methods are limited by data sparsity. Here, the authors introduce SnapATAC, a pipeline to resolve cellular heterogeneity and reveal candidate regulatory elements across different cell populations.Rongxin FangSebastian PreisslYang LiXiaomeng HouJacinta LuceroXinxin WangAmir MotamediAndrew K. ShiauXinzhu ZhouFangming XieEran A. MukamelKai ZhangYanxiao ZhangM. Margarita BehrensJoseph R. EckerBing RenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rongxin Fang
Sebastian Preissl
Yang Li
Xiaomeng Hou
Jacinta Lucero
Xinxin Wang
Amir Motamedi
Andrew K. Shiau
Xinzhu Zhou
Fangming Xie
Eran A. Mukamel
Kai Zhang
Yanxiao Zhang
M. Margarita Behrens
Joseph R. Ecker
Bing Ren
Comprehensive analysis of single cell ATAC-seq data with SnapATAC
description Single cell analysis of transposase-accessible chromatin is deepening our understanding on the origins of cellular diversity, yet methods are limited by data sparsity. Here, the authors introduce SnapATAC, a pipeline to resolve cellular heterogeneity and reveal candidate regulatory elements across different cell populations.
format article
author Rongxin Fang
Sebastian Preissl
Yang Li
Xiaomeng Hou
Jacinta Lucero
Xinxin Wang
Amir Motamedi
Andrew K. Shiau
Xinzhu Zhou
Fangming Xie
Eran A. Mukamel
Kai Zhang
Yanxiao Zhang
M. Margarita Behrens
Joseph R. Ecker
Bing Ren
author_facet Rongxin Fang
Sebastian Preissl
Yang Li
Xiaomeng Hou
Jacinta Lucero
Xinxin Wang
Amir Motamedi
Andrew K. Shiau
Xinzhu Zhou
Fangming Xie
Eran A. Mukamel
Kai Zhang
Yanxiao Zhang
M. Margarita Behrens
Joseph R. Ecker
Bing Ren
author_sort Rongxin Fang
title Comprehensive analysis of single cell ATAC-seq data with SnapATAC
title_short Comprehensive analysis of single cell ATAC-seq data with SnapATAC
title_full Comprehensive analysis of single cell ATAC-seq data with SnapATAC
title_fullStr Comprehensive analysis of single cell ATAC-seq data with SnapATAC
title_full_unstemmed Comprehensive analysis of single cell ATAC-seq data with SnapATAC
title_sort comprehensive analysis of single cell atac-seq data with snapatac
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/18a2c5f660e04078a2e5f322063c59a2
work_keys_str_mv AT rongxinfang comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT sebastianpreissl comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT yangli comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT xiaomenghou comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT jacintalucero comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT xinxinwang comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT amirmotamedi comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT andrewkshiau comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT xinzhuzhou comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT fangmingxie comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT eranamukamel comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT kaizhang comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT yanxiaozhang comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT mmargaritabehrens comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT josephrecker comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
AT bingren comprehensiveanalysisofsinglecellatacseqdatawithsnapatac
_version_ 1718393374197678080

Ejemplares similares