Intestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila

Emerging evidence suggests that gut microbiota influences immune function in the brain and may play a role in neurological diseases. Here, the authors offer in vivo evidence from a Drosophila model that supports a role for gut microbiota in modulating the progression of Alzheimer’s disease.

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Autores principales: Shih-Cheng Wu, Zih-Syuan Cao, Kuo-Ming Chang, Jyh-Lyh Juang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/18ac214b1dd343e297112600a6b26c15
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spelling oai:doaj.org-article:18ac214b1dd343e297112600a6b26c152021-12-02T13:57:32ZIntestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila10.1038/s41467-017-00040-62041-1723https://doaj.org/article/18ac214b1dd343e297112600a6b26c152017-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00040-6https://doaj.org/toc/2041-1723Emerging evidence suggests that gut microbiota influences immune function in the brain and may play a role in neurological diseases. Here, the authors offer in vivo evidence from a Drosophila model that supports a role for gut microbiota in modulating the progression of Alzheimer’s disease.Shih-Cheng WuZih-Syuan CaoKuo-Ming ChangJyh-Lyh JuangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shih-Cheng Wu
Zih-Syuan Cao
Kuo-Ming Chang
Jyh-Lyh Juang
Intestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila
description Emerging evidence suggests that gut microbiota influences immune function in the brain and may play a role in neurological diseases. Here, the authors offer in vivo evidence from a Drosophila model that supports a role for gut microbiota in modulating the progression of Alzheimer’s disease.
format article
author Shih-Cheng Wu
Zih-Syuan Cao
Kuo-Ming Chang
Jyh-Lyh Juang
author_facet Shih-Cheng Wu
Zih-Syuan Cao
Kuo-Ming Chang
Jyh-Lyh Juang
author_sort Shih-Cheng Wu
title Intestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila
title_short Intestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila
title_full Intestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila
title_fullStr Intestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila
title_full_unstemmed Intestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila
title_sort intestinal microbial dysbiosis aggravates the progression of alzheimer’s disease in drosophila
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/18ac214b1dd343e297112600a6b26c15
work_keys_str_mv AT shihchengwu intestinalmicrobialdysbiosisaggravatestheprogressionofalzheimersdiseaseindrosophila
AT zihsyuancao intestinalmicrobialdysbiosisaggravatestheprogressionofalzheimersdiseaseindrosophila
AT kuomingchang intestinalmicrobialdysbiosisaggravatestheprogressionofalzheimersdiseaseindrosophila
AT jyhlyhjuang intestinalmicrobialdysbiosisaggravatestheprogressionofalzheimersdiseaseindrosophila
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