Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature.

Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature.

<h4>Introduction</h4>Inherent and acquired cisplatin resistance reduces the effectiveness of this agent in the management of non-small cell lung cancer (NSCLC). Understanding the molecular mechanisms underlying this process may result in the development of novel agents to enhance the sen...

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Autores principales: Martin P Barr, Steven G Gray, Andreas C Hoffmann, Ralf A Hilger, Juergen Thomale, John D O'Flaherty, Dean A Fennell, Derek Richard, John J O'Leary, Kenneth J O'Byrne
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/18af4cd6dbdb4d73aa78e1b2488d6a3e
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