Genome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis

Abstract Fenneropenaeus chinensis is one of the most important aquaculture species in China. Research on its genomic and genetic structure not only helps us comprehend the genetic basis of complex economic traits, but also offers theoretical guidance in selective breeding. In the present study, a ge...

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Autores principales:	Xianhong Meng, Qiang Fu, Sheng Luan, Kun Luo, Juan Sui, Jie Kong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/18afd0a1a8654a779a847d5f4d5e985e
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spelling	oai:doaj.org-article:18afd0a1a8654a779a847d5f4d5e985e2021-12-02T14:21:11ZGenome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis10.1038/s41598-021-87237-42045-2322https://doaj.org/article/18afd0a1a8654a779a847d5f4d5e985e2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87237-4https://doaj.org/toc/2045-2322Abstract Fenneropenaeus chinensis is one of the most important aquaculture species in China. Research on its genomic and genetic structure not only helps us comprehend the genetic basis of complex economic traits, but also offers theoretical guidance in selective breeding. In the present study, a genome survey sequencing was performed to generate a rough reference genome utilized for groping preliminary genome characteristics and facilitate linkage and quantitative trait locus (QTL) mapping. Linkage mapping was conducted using a reduced-representation sequencing method 2b-RAD. In total, 36,762 SNPs were genotyped from 273 progenies in a mapping family, and a high-resolution linkage map was constructed. The consensus map contained 12,884 markers and spanned 5257.81 cM with an average marker interval of 0.41 cM, which was the first high-resolution genetic map in F. chinensis to our knowledge. QTL mapping and association analysis were carried out in 29 characters including body size, sex and disease resistance. 87 significant QTLs were detected in several traits and they were also evaluated by association analysis. Results of this study provide us valuable suggestions in genetic improvement and breeding of new varieties and also lay a basic foundation for further application of cloning of economic genes in selective breeding program and marker-assisted selection.Xianhong MengQiang FuSheng LuanKun LuoJuan SuiJie KongNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Xianhong Meng Qiang Fu Sheng Luan Kun Luo Juan Sui Jie Kong Genome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis
description	Abstract Fenneropenaeus chinensis is one of the most important aquaculture species in China. Research on its genomic and genetic structure not only helps us comprehend the genetic basis of complex economic traits, but also offers theoretical guidance in selective breeding. In the present study, a genome survey sequencing was performed to generate a rough reference genome utilized for groping preliminary genome characteristics and facilitate linkage and quantitative trait locus (QTL) mapping. Linkage mapping was conducted using a reduced-representation sequencing method 2b-RAD. In total, 36,762 SNPs were genotyped from 273 progenies in a mapping family, and a high-resolution linkage map was constructed. The consensus map contained 12,884 markers and spanned 5257.81 cM with an average marker interval of 0.41 cM, which was the first high-resolution genetic map in F. chinensis to our knowledge. QTL mapping and association analysis were carried out in 29 characters including body size, sex and disease resistance. 87 significant QTLs were detected in several traits and they were also evaluated by association analysis. Results of this study provide us valuable suggestions in genetic improvement and breeding of new varieties and also lay a basic foundation for further application of cloning of economic genes in selective breeding program and marker-assisted selection.
format	article
author	Xianhong Meng Qiang Fu Sheng Luan Kun Luo Juan Sui Jie Kong
author_facet	Xianhong Meng Qiang Fu Sheng Luan Kun Luo Juan Sui Jie Kong
author_sort	Xianhong Meng
title	Genome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis
title_short	Genome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis
title_full	Genome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis
title_fullStr	Genome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis
title_full_unstemmed	Genome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis
title_sort	genome survey and high-resolution genetic map provide valuable genetic resources for fenneropenaeus chinensis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/18afd0a1a8654a779a847d5f4d5e985e
work_keys_str_mv	AT xianhongmeng genomesurveyandhighresolutiongeneticmapprovidevaluablegeneticresourcesforfenneropenaeuschinensis AT qiangfu genomesurveyandhighresolutiongeneticmapprovidevaluablegeneticresourcesforfenneropenaeuschinensis AT shengluan genomesurveyandhighresolutiongeneticmapprovidevaluablegeneticresourcesforfenneropenaeuschinensis AT kunluo genomesurveyandhighresolutiongeneticmapprovidevaluablegeneticresourcesforfenneropenaeuschinensis AT juansui genomesurveyandhighresolutiongeneticmapprovidevaluablegeneticresourcesforfenneropenaeuschinensis AT jiekong genomesurveyandhighresolutiongeneticmapprovidevaluablegeneticresourcesforfenneropenaeuschinensis
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Genome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis

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